Melanoma molecular subtypes: Unifying and paradoxical results Journal Article
| Authors: | Thomas, N. E.; Kanetsky, P. A.; Begg, C. B.; Conway, K.; Berwick, M. |
| Article Title: | Melanoma molecular subtypes: Unifying and paradoxical results |
| Abstract: | In this issue, Hacker and colleagues provide further evidence that molecular subtypes of malignant melanoma may develop along divergent pathways. The authors did not find an association between somatic BRAF-mutant melanoma and germline melanocortin-1 receptor (MC1R) gene status. We discuss this seeming paradox in light of previous studies demonstrating strong associations. © 2010 The Society for Investigative Dermatology. |
| Keywords: | gene mutation; cancer risk; nonhuman; note; cancer diagnosis; dna damage; dna repair; melanoma; sun exposure; nevus; skin neoplasms; genetic association; genetic variability; genotype; pigmentation; gene interaction; molecular typing; melanocortin 1 receptor; receptor, melanocortin, type 1; b raf kinase; proto-oncogene proteins b-raf; elastosis; genotype environment interaction |
| Journal Title: | Journal of Investigative Dermatology |
| Volume: | 130 |
| Issue: | 1 |
| ISSN: | 0022-202X |
| Publisher: | Elsevier Science, Inc. |
| Date Published: | 2010-01-01 |
| Start Page: | 12 |
| End Page: | 14 |
| Language: | English |
| DOI: | 10.1038/jid.2009.332 |
| PUBMED: | 20010862 |
| PROVIDER: | scopus |
| PMCID: | PMC2950747 |
| DOI/URL: | |
| Notes: | --- - "Cited By (since 1996): 1" - "Export Date: 20 April 2011" - "CODEN: JIDEA" - "Source: Scopus" |
