Critical appraisal of outcomes following open radical prostatectomy Journal Article


Authors: Galvin, D. J.; Eastham, J. A.
Article Title: Critical appraisal of outcomes following open radical prostatectomy
Abstract: PURPOSE OF REVIEW: Radical prostatectomy has evolved enormously over the last 25 years. Improvements include the use of smaller incisions, reduced blood loss, shorter hospital stays, and surgical refinement to improve the recovery of continence and potency. In addition, new technologies and minimally invasive techniques with the potential to further improve patient outcomes have been introduced. This article focuses on outcomes with open radical prostatectomy and is not meant to compare open radical prostatectomy and minimally invasive approaches. RECENT FINDINGS: Despite a lack of randomized controlled trials, strong observational cohort studies demonstrate lower rates of positive surgical margins, high 10-year and 15-year biochemical recurrence-free rates, excellent prostate cancer-specific mortality rates, and improved recovery of urinary incontinence and erectile function after open radical prostatectomy. We review publications from the past 24 months regarding oncologic outcome, continence, and erectile function, as well as some earlier manuscripts that emphasize key aspects of open radical prostatectomy. SUMMARY: Today open radical prostatectomy is a less-invasive procedure with low morbidity providing excellent control of clinically localized prostate cancer. Although open radical prostatectomy now accounts for a minority of radical prostatectomies in the United States, the concepts that have improved oncologic and quality-of-life outcomes are equally applicable to minimally invasive procedures. © 2009 Lippincott Williams & Wilkins, Inc.
Keywords: treatment outcome; patient satisfaction; surgical technique; review; cancer recurrence; outcome assessment; methodology; laparoscopic surgery; quality of life; cancer mortality; prostate cancer; prostatic neoplasms; prostate; urine incontinence; prostatectomy; prostate tumor; radical prostatectomy; intermethod comparison; robotics; cancer control; erectile dysfunction; urinary incontinence; outcomes; robotic; sexual function
Journal Title: Current Opinion in Urology
Volume: 19
Issue: 3
ISSN: 0963-0643
Publisher: Lippincott Williams & Wilkins  
Date Published: 2009-05-01
Start Page: 297
End Page: 302
Language: English
DOI: 10.1097/MOU.0b013e328329eb13
PUBMED: 19365894
PROVIDER: scopus
DOI/URL:
Notes: --- - "Cited By (since 1996): 1" - "Export Date: 30 November 2010" - "CODEN: CUOUE" - "Source: Scopus"
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  1. David Jonathan Galvin
    11 Galvin
  2. James Eastham
    537 Eastham