MRI-safe robot for endorectal prostate biopsy Journal Article


Authors: Stoianovici, D.; Kim, C.; Srimathveeravalli, G.; Sebrecht, P.; Petrisor, D.; Coleman, J.; Solomon, S. B.; Hricak, H.
Article Title: MRI-safe robot for endorectal prostate biopsy
Abstract: This paper reports the development of an MRI-Safe robot for direct (interventional) MRI-guided endorectal prostate biopsy. The robot is constructed of nonmagnetic and electrically nonconductive materials, and is electricity free, using pneumatic actuation and optical sensors. Targeting biopsy lesions of MRI abnormality presents substantial clinical potential for the management of prostate cancer. This paper describes MRI-Safe requirements and presents the kinematic architecture, design, and construction of the robot, and a comprehensive set of preclinical tests for MRI compatibility and needle targeting accuracy. The robot has a compact and simple three degree-of-freedom (DoF) structure, two for orienting a needle-guide and one to preset the depth of needle insertion. The actual insertion is performed manually through the guide and up to the preset depth. To reduce the complexity and size of the robot next to the patient, the depth setting DoF is remote. Experimental results show that the robot is safe to use in any MRI environment (MRI-Safe). Comprehensive MRI tests show that the presence and motion of the robot in the MRI scanner cause virtually no image deterioration or signal-to-noise ratio change. Robot's accuracy in bench test, CT-guided in-vitro, MRI-guided in-vitro , and animal tests are 0.37, 1.10, 2.09, and 2.58 mm, respectively. These values are acceptable for clinical use. © 1996-2012 IEEE.
Keywords: prostate biopsy; robot; motor; pneumatic; mri-compatible; mri-safe
Journal Title: IEEE/ASME Transactions on Mechatronics
Volume: 19
Issue: 4
ISSN: 1083-4435
Publisher: IEEE  
Date Published: 2014-08-01
Start Page: 1289
End Page: 1299
Language: English
DOI: 10.1109/tmech.2013.2279775
PROVIDER: scopus
PMCID: PMC4219418
PUBMED: 25378897
DOI/URL:
Notes: IEEE ASME Trans Mechatron -- Export Date: 2 June 2014 -- CODEN: IATEF -- Source: Scopus
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  1. Jonathan Coleman
    341 Coleman
  2. Stephen Solomon
    422 Solomon
  3. Hedvig Hricak
    419 Hricak