Turning ecology and evolution against cancer Journal Article


Authors: Korolev, K. S.; Xavier, J. B.; Gore, J.
Article Title: Turning ecology and evolution against cancer
Abstract: The fight against cancer has drawn researchers from a wide variety of disciplines, ranging from molecular biology to physics, but the perspective of an ecological theorist has been mostly overlooked. By thinking about the cells that make up a tumour as an endangered species, cancer vulnerabilities become more apparent. Studies in conservation biology and microbial experiments indicate that extinction is a complex phenomenon, which is often driven by the interaction of ecological and evolutionary processes. Recent advances in cancer research have shown that tumours, like species striving for survival, harbour intricate population dynamics, which suggests the possibility to exploit the ecology of tumours for treatment. © 2014 Macmillan Publishers Limited.
Journal Title: Nature Reviews Cancer
Volume: 14
Issue: 5
ISSN: 1474-175X
Publisher: Nature Publishing Group  
Date Published: 2014-05-01
Start Page: 371
End Page: 380
Language: English
DOI: 10.1038/nrc3712
PROVIDER: scopus
PUBMED: 24739582
DOI/URL:
Notes: Nat. Rev. Cancer -- Export Date: 2 June 2014 -- CODEN: NRCAC -- Source: Scopus
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