The Hsp90 inhibitor, 17-Allylamino-17-Demethoxygeldanamycin (17AAG) abrogates the G(2)/M DNA damage checkpoint and induces apoptosis selectively in p53-defective colon cancer cells by down-regulating both Chk1 and Wee1 Meeting Abstract

  


Authors: Tse, A. N.; Sheikh, T. N.; Schwartz, G. K.
Abstract Title: The Hsp90 inhibitor, 17-Allylamino-17-Demethoxygeldanamycin (17AAG) abrogates the G(2)/M DNA damage checkpoint and induces apoptosis selectively in p53-defective colon cancer cells by down-regulating both Chk1 and Wee1
Meeting Title: 96th Annual Meeting of the American Association for Cancer Research (AACR)
Journal Title: Cancer Research
Volume: 65
Issue: 9 Suppl.
Meeting Dates: 2005 Apr 16-20
Meeting Location: Anaheim, CA
ISSN: 0008-5472
Publisher: American Association for Cancer Research  
Date Published: 2005-05-01
Start Page: 1449
Language: English
ACCESSION: BIOSIS:PREV200700274247
PROVIDER: biosis
DOI/URL:

http://gateway.isiknowledge.com/gateway/Gateway.cgi?&GWVersion=2&SrcAuth=CustomerName&SrcApp=CustomerName&DestLinkType=FullRecord&KeyUT=BIOSIS:PREV200700274247&DestApp=BIOSIS
Notes: Meeting abstract: 6159 -- In: Proceedings of the 96th Annual Meeting of the American Association for Cancer Research -- Anaheim, CA, USA -- April 16 -20, 2005 -- Amer Assoc Canc Res -- Source: Biosis