Salvage therapy for relapsed and refractory Hodgkin lymphoma Book Section


Authors: Yahalom, J.; Rimner, A.; Tsang, R. W.
Editors: Specht, L.; Yahalom, J.
Article/Chapter Title: Salvage therapy for relapsed and refractory Hodgkin lymphoma
Abstract: Patients with Hodgkin lymphoma (HL) who remain refractory to their chemotherapy-based primary treatment or relapse after obtaining a remission still have a very good chance of cure with appropriate salvage therapy. Most will be good candidates for high-dose therapy (HDT) programs that are supported with infusion of their autologous peripheral blood stem cells. Most programs start with standard-dose chemotherapy for response re-induction in an attempt to maximize tumor reduction prior to HDT. In special circumstances, other salvage options with standard-dose chemotherapy and/or radiation therapy (RT) are available and are also discussed below. Radiation therapy should play a major role in the salvage effort of chemotherapy or combined-modality failures, as often its benefits have not been exploited with the primary treatment. Methods of integrating RT effectively and safely into the salvage effort are discussed in this chapter. © 2011 Springer-Verlag Berlin Heidelberg.
Book Title: Radiotherapy for Hodgkin Lymphoma
ISBN: 978-3-540-78455-5
Publisher: Springer Berlin Heidelberg  
Publication Place: Heidelberg, Germany
Date Published: 2011-01-01
Start Page: 31
End Page: 44
Language: English
DOI: 10.1007/978-3-540-78944-4_4
PROVIDER: scopus
DOI/URL:
Notes: Book chapter: 4 -- 9783540784555 (ISBN) -- Export Date: 3 March 2014 -- Source: Scopus
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  1. Joachim Yahalom
    625 Yahalom
  2. Andreas Rimner
    524 Rimner