Abstract: |
The anal canal possesses complex anatomy and histology and gives rise to a variety of tumor types. Challenging issues remain with regard to both the pathologic diagnosis and the clinical management of these tumors. Objectives.-To provide an updated overview of the histogenesis, clinical and pathologic characteristics, diagnostic terminology, and relevant clinical management of the various types of anal canal tumors. Data Sources.-Recent literature on clinical and pathologic characteristics of anal canal tumors. Conclusions.-Although most anal canal tumors are of squamous lineage, a complex variety ofother tumors also occurs. Recognition of such diverse tumor entitieswill allow accurate pathologic diagnosis and most optimal clinical management. |