ACR Appropriateness Criteria® - Anal cancer Journal Article


Authors: Hong, T. S.; Pretz, J. L.; Herman, J. M.; Abdel-Wahab, M.; Azad, N.; Blackstock, A. W.; Das, P.; Goodman, K. A.; Jabbour, S. K.; Jones, W. E. 3rd; Konski, A. A.; Koong, A. C.; Rodriguez-Bigas, M.; Small, W. Jr; Thomas, C. R. Jr; Zook, J.; Suh, W. W.
Article Title: ACR Appropriateness Criteria® - Anal cancer
Abstract: The management of anal cancer is driven by randomized and nonrandomized clinical trials. However, trials may present conflicting conclusions. Furthermore, different clinical situations may not be addressed in certain trials because of eligibility inclusion criteria. Although prospective studies point to the use of definitive 5-fluorouracil and mitomycin C-based chemoradiation as a standard, some areas remain that are not well defined. In particular, management of very early stage disease, radiation dose, and the use of intensity-modulated radiation therapy remain unaddressed by phase III studies. The American College of Radiology (ACR) Appropriateness Criteria® are evidence-based guidelines for specific clinical conditions that are reviewed every 2 years by a multidisciplinary expert panel. The guideline development and review include an extensive analysis of current medical literature from peer-reviewed journals and the application of a well-established consensus methodology (modified Delphi) to rate the appropriateness of imaging and treatment procedures by the panel. In those instances where evidence is lacking or not definitive, expert opinion may be used to recommend imaging or treatment. © 2014 American College of Radiology. All rights reserved.
Keywords: survival rate; unclassified drug; overall survival; intensity modulated radiation therapy; squamous cell carcinoma; cisplatin; fluorouracil; radiation dose; chemotherapy; cancer staging; positron emission tomography; follow up; antineoplastic agent; sentinel lymph node biopsy; computer assisted tomography; evidence based practice; histology; distant metastasis; imrt; brachytherapy; external beam radiotherapy; cancer control; mitomycin; anus cancer; chemoradiation; randomized controlled trial (topic); phase 2 clinical trial (topic); phase 3 clinical trial (topic); anal cancer; interstitial radiation; cancer prognosis; human; article; rtog 0529
Journal Title: Gastrointestinal Cancer Research
Volume: 7
Issue: 1
ISSN: 1934-7820
Publisher: International Society of Gastrointestinal Oncology  
Date Published: 2014-01-01
Start Page: 4
End Page: 14
Language: English
PROVIDER: scopus
PMCID: PMC3924766
PUBMED: 24558509
DOI/URL:
Notes: Export Date: 2 April 2014 -- Source: Scopus
Citation Impact
MSK Authors
  1. Karyn A Goodman
    257 Goodman