Ommaya reservoir infections: A 16-year retrospective analysis Journal Article
| Authors: | Mead, P. A.; Safdieh, J. E.; Nizza, P.; Tuma, S.; Sepkowitz, K. A. |
| Article Title: | Ommaya reservoir infections: A 16-year retrospective analysis |
| Abstract: | Objectives: Ommaya reservoirs (OmR) are used in the treatment of cancer yet risk factors and outcome of infection are not well characterized. We therefore examined our experience with this device. Methods: Using administrative databases, we identified all patients with OmR in situ between 1993 and 2008 at Memorial Sloan-Kettering Cancer Center. Charts were reviewed for laboratory, demographic, and clinical information. Results: During the study period, 616 patients with OmRs received care at MSKCC comprising 462,467 Ommaya-days. 34 patients with OmR infection were identified (5.5% of patients, 0.74 infections per 10,000 Ommaya-days). 32% of infections occurred within 30 days of OmR placement. Most (74%) OmR infections occurring after 30 days post-placement were associated with OmR access in the preceding 30 days. Recovered organisms included coagulase-negative staphylococci (56%) and Propionibacterium acnes (24%). 70% of patients had fever and/or headache and 69% had cerebrospinal fluid pleocytosis. 50% of patients had the reservoir removed during treatment of the infection. Conclusions: OmR infection occurs in one of every 20 persons with the device. A third of the infections appear related to OmR placement while the remainder may occur at any time and usually are associated with recent reservoir access. Treatment often includes device removal. © 2013 The British Infection Association. |
| Keywords: | infection; central nervous system; meningitis; cerebral ventriculitis; indwelling catheters; ommaya |
| Journal Title: | Journal of Infection |
| Volume: | 68 |
| Issue: | 3 |
| ISSN: | 0163-4453 |
| Publisher: | W.B. Saunders Co. |
| Date Published: | 2014-03-01 |
| Start Page: | 225 |
| End Page: | 230 |
| Language: | English |
| DOI: | 10.1016/j.jinf.2013.11.014 |
| PROVIDER: | scopus |
| PUBMED: | 24321561 |
| DOI/URL: | |
| Notes: | Export Date: 3 March 2014 -- CODEN: JINFD -- Source: Scopus |
Altmetric
Citation Impact
BMJ Impact Analytics
Related MSK Work