Diffusion-weighted MRI of the prostate at 3.0 T: Comparison of endorectal coil (ERC) MRI and phased-array coil (PAC) MRI - The impact of SNR on ADC measurement Journal Article


Authors: Mazaheri, Y.; Vargas, H. A.; Nyman, G.; Shukla-Dave, A.; Akin, O.; Hricak, H.
Article Title: Diffusion-weighted MRI of the prostate at 3.0 T: Comparison of endorectal coil (ERC) MRI and phased-array coil (PAC) MRI - The impact of SNR on ADC measurement
Abstract: Purpose: To compare ADC values measured from diffusion-weighted MR (DW-MR) images of the prostate obtained with both endorectal and phased-array coils (ERC + PAC) to those from DW-MRI images obtained with an eight-channel torso phased-array coil (PAC) at 3.0 T. Methods: The institutional review board issued a waiver of informed consent for this HIPAA-compliant study. Twenty-five patients with biopsy-proven prostate cancer underwent standard 3-T MRI using 2 different coil arrangements (ERC + PAC and PAC only) in the same session. DW-MRI at five b-values (0, 600, 1000, 1200, and 1500 s/mm2) were acquired using both coil arrangements. On b = 0 images, signalto- noise ratios (SNRs) were measured as the ratio of the mean signal from PZ and TZ ROIs to the standard deviation from the mean signal in an artifact-free ROI in the rectum. Matching regions-of-interest (ROIs) were identified in the peripheral zone and transition zone on ERC-MRI and PAC-MRI. For each ROI, mean ADC values for all zero and non-zero b-value combinations were computed. Results: Mean SNR with ERC-MRI at PZ (66.33 ± 27.07) and TZ (32.69 ± 12.52) was 9.27 and 5.52 times higher than with PAC-MRI ((7.32 ± 2.30) and (6.13 ± 1.56), respectively) (P < 0.0001 for both). ADCs from DW-MR images obtained with all b-values in the PZ and TZ were significantly lower with PAC-MRI than with ERC-MRI (P < 0.001 for all). Conclusion: Lower SNR of DW-MR images of the prostate obtained with a PAC can significantly decrease ADC values at higher b-values compared to similar measurements obtained using the ERC. To address these requirements, clinical MR systems should have image processing capabilities which incorporate the noise distribution. © 2013 Elsevier Ireland Ltd.
Keywords: prostate; diffusion-weighted mri (dw-mri); endorectal coil (erc); phased-array coil (pac); signal-to-noise ratio (snr)
Journal Title: European Journal of Radiology
Volume: 82
Issue: 10
ISSN: 0720-048X
Publisher: Elsevier Ireland Ltd.  
Date Published: 2013-10-01
Start Page: e515
End Page: e520
Language: English
DOI: 10.1016/j.ejrad.2013.04.041
PROVIDER: scopus
PUBMED: 23810189
DOI/URL:
Notes: Cited By (since 1996):1 -- Export Date: 3 March 2014 -- CODEN: EJRAD -- Source: Scopus
Altmetric Score
MSK Authors
  1. Hedvig Hricak
    335 Hricak
  2. Amita Dave
    83 Dave
  3. Oguz Akin
    180 Akin
  4. Charles Nyman
    5 Nyman