A case of renal cell carcinoma after successful treatment of Wilms tumor Journal Article


Authors: Rich, B. S.; McEvoy, M. P.; LaQuaglia, M. P.
Article Title: A case of renal cell carcinoma after successful treatment of Wilms tumor
Abstract: This case report documents the eighth reported case of renal cell carcinoma (RCC) occurring after treatment of Wilms tumor. Although secondary malignancies after treatment of Wilms tumors are not infrequent, RCC as the second malignancy is rare. We discuss a 17-year-old girl whose RCC was diagnosed 12.5 years after diagnosis of a Wilms tumor. In addition, we review the literature on the subject. Renal cell carcinoma has been proposed as a consequent of chemoradiation; however, a genetic susceptibility must be considered. Because it is routine to assess the functional status of the remaining solitary kidney by annual ultrasonography, we recommend assessing for the presence of secondary renal malignancies and perhaps continuing routine ultrasounds long-term. © 2010 Elsevier Inc. All rights reserved.
Keywords: adolescent; treatment outcome; cancer surgery; case report; doxorubicin; cancer combination chemotherapy; cancer radiotherapy; radiation dose; nuclear magnetic resonance imaging; follow up; cancer diagnosis; laparotomy; computer assisted tomography; tumor volume; etoposide; cyclophosphamide; vincristine; renal cell carcinoma; kidney carcinoma; kidney neoplasms; ifosfamide; carcinoma, renal cell; dactinomycin; cancer epidemiology; neoplasms, second primary; liver biopsy; nephroblastoma; cervical lymphadenopathy; wilms tumor; secondary malignancy; adrenalectomy
Journal Title: Journal of Pediatric Surgery
Volume: 45
Issue: 9
ISSN: 0022-3468
Publisher: W.B. Saunders Co-Elsevier Inc.  
Date Published: 2010-09-01
Start Page: 1883
End Page: 1886
Language: English
DOI: 10.1016/j.jpedsurg.2010.06.032
PUBMED: 20850637
PROVIDER: scopus
DOI/URL:
Notes: --- - "Export Date: 20 April 2011" - "CODEN: JPDSA" - "Source: Scopus"
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  1. Maureen Patricia Mcevoy
    10 Mcevoy
  2. Barrie S Rich
    14 Rich