Role of short-term antibiotic therapy at the moment of catheter removal after laparoscopic radical prostatectomy Journal Article
| Authors: | Pinochet, R; Nogueira, L.; Cronin, A. M.; Katz, D.; Rabbani, F.; Guillonneau, B.; Touijer, K. |
| Article Title: | Role of short-term antibiotic therapy at the moment of catheter removal after laparoscopic radical prostatectomy |
| Abstract: | Objective: To assess the role of short-term antibiotic therapy (ABT) in preventing urinary tract infection (UTI) after catheter removal following laparoscopic radical prostatectomy (LRP). Methods: 729 consecutive patients underwent LRP by one of two surgeons. One surgeon systematically prescribed a 3-day course of ABT (ciprofloxacin) starting the day before catheter removal; the other surgeon did not. The groups were compared for the incidence of symptomatic UTI occurring within 6 weeks after catheter removal. Results: ABT was given to 261 of 713 patients (37%), while the remaining 452 patients (63%) did not receive ABT. After catheter removal, UTI was observed less frequently among patients receiving ABT: 3.1 vs. 7.3% in those not receiving ABT (p = 0.019). A number needed to treat to prevent 1 UTI is 24. Hospital readmission for febrile UTI was observed only in patients who did not receive ABT (n = 5, 1.1 vs. 0%, p = 0.16). One would need to prescribe ABT for 91 LRP patients to prevent 1 case of febrile UTI. Conclusions: ABT at the time of catheter removal reduced the risk of postoperative UTI after LRP. One would need to prescribe ABT to 24 patients to prevent 1 case of UTI. Copyright © 2010 S. Karger AG, Basel. |
| Keywords: | adult; controlled study; major clinical study; laparoscopic surgery; bleeding; morbidity; deep vein thrombosis; hematuria; fever; postoperative complication; prescription; length of stay; prostate; prostatectomy; escherichia coli; operation duration; surgeon; surgical infection; urinary tract infection; ciprofloxacin; blood transfusion; urinary frequency; surgical mortality; emergency care; urinary urgency; hospital readmission; enterococcus; staphylococcus aureus; risk reduction; antibiotic prophylaxis; ileus; urine retention; infection risk; burning sensation; dysuria; catheter removal; anastomosis leakage; obturator nerve; cefazolin; catheter-related infection; laparoscopic radical prostatectomy; enterobacter cloacae; klebsiella; klebsiella oxytoca; lymphocele; nerve paralysis; pelvis abscess; pseudomonas; ureter injury; urine culture |
| Journal Title: | Urologia Internationalis |
| Volume: | 85 |
| Issue: | 4 |
| ISSN: | 0042-1138 |
| Publisher: | S. Karger AG |
| Date Published: | 2010-01-01 |
| Start Page: | 415 |
| End Page: | 420 |
| Language: | English |
| DOI: | 10.1159/000321094 |
| PROVIDER: | scopus |
| PUBMED: | 21099192 |
| DOI/URL: | |
| Notes: | --- - "Export Date: 20 April 2011" - "CODEN: URINA" - "Source: Scopus" |
Altmetric
Citation Impact
BMJ Impact Analytics
MSK Authors
Related MSK Work