Accuracy analysis in MRI-guided robotic prostate biopsy Journal Article


Authors: Xu, H.; Lasso, A.; Guion, P.; Krieger, A.; Kaushal, A.; Singh, A. K.; Pinto, P. A.; Coleman, J.; Grubb, R. L. 3rd; Lattouf, J. B.; Menard, C.; Whitcomb, L. L.; Fichtinger, G.
Article Title: Accuracy analysis in MRI-guided robotic prostate biopsy
Abstract: Purpose: To assess retrospectively the clinical accuracy of an magnetic resonance imaging-guided robotic prostate biopsy system that has been used in the US National Cancer Institute for over 6 years. Methods: Series of 2D transverse volumetric MR image slices of the prostate both pre (high-resolution T2-weighted)- and post (low-resolution)- needle insertions were used to evaluate biopsy accuracy. A three-stage registration algorithm consisting of an initial two-step rigid registration followed by a B-spline deformable alignment was developed to capture prostate motion during biopsy. The target displacement (distance between planned and actual biopsy target), needle placement error (distance from planned biopsy target to needle trajectory), and biopsy error (distance from actual biopsy target to needle trajectory) were calculated as accuracy assessment. Results: A total of 90 biopsies from 24 patients were studied. The registrations were validated by checking prostate contour alignment using image overlay, and the results were accurate to within 2 mm. The mean target displacement, needle placement error, and clinical biopsy error were 5.2, 2.5, and 4.3 mm, respectively. Conclusion: The biopsy error reported suggests that quantitative imaging techniques for prostate registration and motion compensation may improve prostate biopsy targeting accuracy. © 2013 CARS.
Keywords: prostate biopsy; image registration; accuracy validation; mri-guidance
Journal Title: International Journal of Computer Assisted Radiology and Surgery
Volume: 8
Issue: 6
ISSN: 1861-6410
Publisher: Springer  
Date Published: 2013-11-01
Start Page: 937
End Page: 944
Language: English
DOI: 10.1007/s11548-013-0831-9
PROVIDER: scopus
PUBMED: 23532560
PMCID: PMC4139961
DOI/URL:
Notes: Export Date: 2 January 2014 -- Source: Scopus
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  1. Jonathan Coleman
    343 Coleman