The importance of subclonal genetic events in MDS Journal Article


Authors: Bejar, R.; Abdel-Wahab, O.
Article Title: The importance of subclonal genetic events in MDS
Abstract: In this issue of Blood, Papaemmanuil et al present results from the largest single targeted sequencing effort in myelodysplastic syndrome (MDS) to date both in terms of number of patients studied (738 patients, of which 603 had MDS) and genes sequenced (111 genes). © 2013 by The American Society of Hematology.
Keywords: unclassified drug; acute granulocytic leukemia; gene sequence; overall survival; sequence analysis; somatic mutation; pathogenesis; review; cancer growth; disease free survival; phenotype; disease association; molecular dynamics; protein; genetic association; gene frequency; cytogenetics; patient monitoring; mutational analysis; protein p53; dna methylation; myelodysplastic syndrome; fluorescence in situ hybridization; scoring system; chronic lymphatic leukemia; rna splicing; transcription factor runx1; oncogene c kit; demethylation; oncogene n ras; cancer prognosis; exome; asxl1 protein; srsf2 protein; prognosis; human; priority journal; whole genome sequencing
Journal Title: Blood
Volume: 122
Issue: 22
ISSN: 0006-4971
Publisher: American Society of Hematology  
Date Published: 2013-11-21
Start Page: 3550
End Page: 3551
Language: English
DOI: 10.1182/blood-2013-09-527655
PROVIDER: scopus
PUBMED: 24263953
DOI/URL:
Notes: Export Date: 2 January 2014 -- CODEN: BLOOA -- Source: Scopus
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