Medroxyprogesterone acetate treatment for sexually inappropriate behavior in a patient with frontotemporal dementia Journal Article


Authors: Balasubramaniam, M.; Clark, L. M.; Jensen, T. P.; Alici, Y.
Article Title: Medroxyprogesterone acetate treatment for sexually inappropriate behavior in a patient with frontotemporal dementia
Abstract: Limited information is available on efficacious therapies for the treatment of sexually inappropriate behavior (SIB) in individuals with frontotemporal dementia (FTD), despite its high prevalence. The authors present the case of an elderly male resident with FTD who was transferred to their state psychiatric facility from an assisted living facility because of concerns of worsening SIB. He was successfully treated with medroxyprogesterone acetate (MPA) after having an unsatisfactory response to a variety of psychopharmacologic agents and behavioral interventions. This case highlights the use of MPA as a safe and efficacious treatment for this behavior, and the authors provide recommendations for its use to target SIB in patients with FTD. The case also highlights the complementary role of behavioral interventions.
Keywords: dementia; frontotemporal dementia; behavioral interventions; hypersexual behavior; medroxyprogesterone acetate (mpa); sexually inappropriate behavior
Journal Title: Annals of Long-Term Care
Volume: 21
Issue: 11
ISSN: 1524-7929
Publisher: HMP Communications  
Date Published: 2013-11-01
Start Page: 30
End Page: 36
Language: English
PROVIDER: scopus
DOI/URL:
Notes: Export Date: 2 January 2014 -- CODEN: ALTCF -- Source: Scopus