Mixed acinar-endocrine carcinoma of the pancreas Journal Article
| Authors: | Ohike, N.; Basturk, O.; Klöppel, G.; Morohoshi, T. |
| Article Title: | Mixed acinar-endocrine carcinoma of the pancreas |
| Abstract: | Mixed acinar-(neuro)endocrine carcinoma (MAEC) is a malignant epithelial neoplasm of the pancreas exhibiting both acinar and (neuro)endocrine differentiation and is diagnosed when each component constitutes a significant proportion (25%-30%) of the neoplasm. Histologically, many are similar to acinar cell carcinoma (ACC), with the mixed differentiation detected by immunohistochemistry and share many clinicopathological features with ACC. Therefore, MAEC has been considered a variant of ACC. This review addresses the pathology, clinical features, and histogenesis of MAEC and its differential diagnosis. © 2010 by Lippincott Williams & Wilkins. |
| Keywords: | immunohistochemistry; adult; cancer chemotherapy; human tissue; clinical feature; histopathology; review; case report; pancreas; electron microscopy; differential diagnosis; ca 19-9 antigen; cell differentiation; pathology; pancreas carcinoma; liver metastasis; autopsy; epigastric pain; histogenesis; endocrine tumor; mixed acinar-endocrine carcinoma |
| Journal Title: | Pathology Case Reviews |
| Volume: | 15 |
| Issue: | 6 |
| ISSN: | 1082-9784 |
| Publisher: | Lippincott Williams & Wilkins |
| Date Published: | 2010-11-01 |
| Start Page: | 205 |
| End Page: | 209 |
| Language: | English |
| DOI: | 10.1097/PCR.0b013e3181ffb18f |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | --- - "Export Date: 20 April 2011" - "Source: Scopus" |
