Injection anxiety and pain in men using intracavernosal injection therapy after radical pelvic surgery Journal Article
| Authors: | Nelson, C. J.; Hsiao, W.; Balk, E.; Narus, J.; Tal, R.; Bennett, N. E.; Mulhall, J. P. |
| Article Title: | Injection anxiety and pain in men using intracavernosal injection therapy after radical pelvic surgery |
| Abstract: | Introduction: Intracavernosal injection (ICI) therapy is a well-recognized treatment strategy with high success rates for men with erectile dysfunction. Despite this, injection anxiety and pain related to injection are significant barriers to its use. Aims: This study aims to examine injection anxiety and injection pain in patients using ICI. Methods: Men starting ICI therapy post radical pelvic surgery completed questionnaires at initial visit, at each of the two ICI training sessions and at a 4-month follow-up visit. Main Outcome Measures: Injection Anxiety Scale, Injection Pain Scale, Injection Reaction Inventory, and the Erectile Function Domain of the International Index of Erectile Function. Results: Average age of the 68 men was 60±8 years. At 4 months, the self-reported frequency of ICI use was: 29% <1/week, 26% 1/week, 40% 2/week, and 5% 3/week. Mean injection anxiety score at first injection was 5.7±2.8 (range 0-10) and significantly decreased to a 4.1±3 at 4 months (P<0.001). At first injection, 65% reported high injection anxiety (≥5) and this significantly decreased to 42% (P=0.003) at 4 months. Anxiety at first injection was negatively related to ICI frequency at 4 months (r=-0.23, P=0.08). Mean injection pain score at first injection was low (2.2±1.8, range 0-10) and 59% rated injection pain ≤2. Injection pain remained consistent across time periods. At first injection, injection anxiety (assessed prior to injection) was related to injection pain (r=0.21, P=0.04) and subjects (n=21) who reported high injection anxiety (≥5) across time points, reported an increase in injection pain scores from first injection to 4 months (2.7 vs. 3.7, P=0.05). Conclusions: Although injection anxiety decreased with ICI use, mean injection anxiety remained at a moderate level (4.4) and 42% of men continued to report "high" injection anxiety at 4 months. While injection pain was low, injection anxiety and pain were related. These data suggest the need for a psychological intervention to help lower injection anxiety related to ICI. © 2013 International Society for Sexual Medicine. |
| Keywords: | adult; major clinical study; follow up; pain; prostate cancer; questionnaire; prostatectomy; cystectomy; anxiety; erectile dysfunction; pain assessment; drug delivery system; pelvis surgery; clinical assessment tool; international index of erectile function; intracavernosal injection; injection pain; injection anxiety; injection anxiety scale; injection pain scale; injection reaction inventory |
| Journal Title: | Journal of Sexual Medicine |
| Volume: | 10 |
| Issue: | 10 |
| ISSN: | 1743-6095 |
| Publisher: | Elsevier Inc. |
| Date Published: | 2013-10-01 |
| Start Page: | 2559 |
| End Page: | 2565 |
| Language: | English |
| DOI: | 10.1111/jsm.12271 |
| PROVIDER: | scopus |
| PUBMED: | 23898886 |
| DOI/URL: | |
| Notes: | --- - "Export Date: 2 December 2013" - "Source: Scopus" |
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