Outcome of resection of infratemporal fossa tumors Journal Article


Authors: Givi, B.; Liu, J.; Bilsky, M.; Mehrara, B.; Disa, J.; Pusic, A.; Cordeiro, P.; Shah, J. P.; Kraus, D. H.
Article Title: Outcome of resection of infratemporal fossa tumors
Abstract: Background A variety of tumors arise in or extend to the infratemporal fossa. We investigated the outcome of surgical management of these tumors. Methods We conducted a retrospective review of a craniofacial approach to resection of infratemporal fossa tumors from 1992 to 2008 in a cancer center. Results Forty-three patients underwent resection of a infratemporal fossa tumors (68% men). Median age was 46 years (range, 1-81 years). The most common pathology was sarcoma (13; 30%). Twenty-two tumors (51%) were recurrent. Twenty patients (46%) underwent resection of tumors from the infratemporal fossa, 5 (12%) required resection of the anterior skull base, and 18 (42%) required orbital exenteration, additionally. Thirty-one patients (72%) required reconstruction with free tissue transfer. Twenty-seven patients (62.8%) required further treatment with radiation and/or chemotherapy. Complications occurred in 9 patients (21%). Six patients (14%) underwent salvage operations. Median follow-up was 24 months. Median overall survival and 3-year survival were 40 months and 59.6%. Conclusion Tumors involving the infratemporal fossa can be resected with acceptable morbidity and long-term survival. © 2013 Wiley Periodicals, Inc.
Keywords: survival; adolescent; adult; cancer chemotherapy; cancer survival; child; clinical article; preschool child; school child; treatment outcome; aged; cancer surgery; overall survival; conference paper; cancer radiotherapy; follow up; antineoplastic agent; infant; chemoradiotherapy; skull tumor; surgical treatment; infratemporal fossa; skull base tumors; infratemporal fossa tumor
Journal Title: Head & Neck
Volume: 35
Issue: 11
ISSN: 1043-3074
Publisher: John Wiley & Sons, Inc.  
Date Published: 2013-11-01
Start Page: 1567
End Page: 1572
Language: English
DOI: 10.1002/hed.23186
PROVIDER: scopus
PUBMED: 23322409
DOI/URL:
Notes: --- - "Export Date: 2 December 2013" - "CODEN: HEANE" - "Source: Scopus"
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MSK Authors
  1. Dennis Kraus
    268 Kraus
  2. Joseph Disa
    263 Disa
  3. Andrea Pusic
    300 Pusic
  4. Mark H Bilsky
    319 Bilsky
  5. Babak Mehrara
    449 Mehrara
  6. Peter G Cordeiro
    283 Cordeiro
  7. Jatin P Shah
    721 Shah