Citizens' perspectives on personalized medicine: A qualitative public deliberation study Journal Article

Authors: Bombard, Y.; Abelson, J.; Simeonov, D.; Gauvin, F. P.
Article Title: Citizens' perspectives on personalized medicine: A qualitative public deliberation study
Abstract: Our objective was to explore citizens' informed and reasoned values and expectations of personalized medicine, a timely yet novel genomics policy issue. A qualitative, public deliberation study was undertaken using a citizens' reference panel on health technologies, established to provide input to the health technology assessment process in Ontario, Canada. The citizens' panel consisted of five women and nine men, aged 18-71 years, with one member selected from each health authority region. There were shared expectations among the citizens' panel members for the potential of personalized medicine technologies to improve care, provided they are deemed clinically valid and effective. These expectations were tempered by concerns about value for money and the possibility that access to treatment may be limited by personalized medicine tests used to stratify patients. Although they questioned the presumed technological imperative presented by personalized medicine technologies, they called for increased efforts to prepare the health-care system to effectively integrate these technologies. This study represents an early but important effort to explore public values toward personalized medicine. This study also provides evidence of the public's ability to form coherent judgments about a new policy issue. Concerned that personalized tests might be used to ration care, they suggested that treatment should be made available if patients wanted it, irrespective of tests that indicate little benefit. This issue raises clinical and policy challenges that may undermine the value of personalized medicine. Further efforts to deliberate with the public are warranted to inform effective, efficient and equitable translation of personalized medicine.© 2013 Macmillan Publishers Limited.
Keywords: adult; controlled study; aged; health care quality; health policy; medical technology; genomics; health care system; expectation; clinical decision making; clinical effectiveness; health; canada; health care access; personalized medicine; hospital policy; deliberative methods; health technology assessment; public engagement; genomic testing; authority; citizenship; money
Journal Title: European Journal of Human Genetics
Volume: 21
Issue: 11
ISSN: 1018-4813
Publisher: Nature Publishing Group  
Date Published: 2013-11-01
Start Page: 1197
End Page: 1201
Language: English
DOI: 10.1038/ejhg.2012.300
PROVIDER: scopus
PMCID: PMC3798829
PUBMED: 23340511
Notes: --- - Cited By (since 1996):1 - "Export Date: 2 December 2013" - "CODEN: EJHGE" - "Source: Scopus"
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  1. Yvonne Bombard
    11 Bombard
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