The pleura in health and disease Journal Article
| Authors: | Murali, R.; Park, K.; Leslie, K. O. |
| Article Title: | The pleura in health and disease |
| Abstract: | A wide variety of local, regional, and systemic diseases may have pleural manifestations. The scope of this pathology encompasses a wide spectrum ranging from minimal inflammatory changes to highly malignant neoplasms. An overview of the normal structure of the pleura is provided, along with the diseases that may be encountered. Pleural specimens from patients with pneumothorax are rarely encountered by pathologists. In contrast, pathologists frequently receive pleural specimens showing evidence of inflammation, repair, or neoplasm. In these circumstances, an awareness of less common (and often clinically highly important) conditions such as epithelioid hemangioendothelioma and primary pleural malignant mesothelioma is essential. Knowledge of the clinical setting (e.g., disease tempo) and radiological picture (e.g., laterality) is often of great value to the pathologist in arriving at a correct diagnosis. Similarly, knowledge of the normal anatomical considerations and familiarity with the expected pleural histopathology for the most clinically relevant pleural diseases are critical assets for pulmonary physicians in providing optimal care for their patients. Copyright © 2010 by Thieme Medical Publishers, Inc. |
| Keywords: | immunohistochemistry; histopathology; nonhuman; methotrexate; outcome assessment; neoplasms; tumor localization; infection; abdominal abscess; carcinoembryonic antigen; amyloidosis; pathology; angiosarcoma; fibrosarcoma; pneumothorax; escherichia coli; cystic fibrosis; tumor cell; pleura mesothelioma; mesothelioma; bleomycin; sepsis; atelectasis; pleura effusion; interstitial lung disease; pleura fluid; tumor growth; staphylococcus aureus; cytokeratin 5; cytokeratin 6; mitomycin; awareness; streptococcus pneumoniae; lung fibrosis; thorax injury; pleura; pathologist; monoclonal antibody d2-40; pleurisy; thyroid transcription factor 1; thrombomodulin; fusobacterium nucleatum; vimentin; hemangioendothelioma; coccidioidomycosis; disease; histiocytosis x; pleura disease; thoracocentesis; amiodarone; bromocriptine; cd15 antigen; ergometrine; ergotamine; methysergide; oxprenolol; practolol; adenomatoid tumor; bacteroides; clostridium; emphysema; esophagus rupture; granulomatous inflammation; infectious pneumonia; loeffler pneumonia; lung barotrauma; lung granuloma; lung sarcoma; lymphangioleiomyomatosis; paragonimiasis; pleura biopsy; pleura empyema; pleura plaque; pleural fibrosis; pneumoconiosis; pneumocystis; spleen injury; spontaneous pneumothorax; transthoracic aspiration; transthoracic biopsy; tuberculous pleurisy |
| Journal Title: | Seminars in Respiratory and Critical Care Medicine |
| Volume: | 31 |
| Issue: | 6 |
| ISSN: | 1069-3424 |
| Publisher: | Thieme Publishing |
| Date Published: | 2010-12-01 |
| Start Page: | 649 |
| End Page: | 673 |
| Language: | English |
| DOI: | 10.1055/s-0030-1269826 |
| PROVIDER: | scopus |
| PUBMED: | 21213198 |
| DOI/URL: | |
| Notes: | --- - "Export Date: 20 April 2011" - "CODEN: SRCCE" - "Source: Scopus" |
