Magnetic resonance imaging for screening, diagnosis, and eligibility for breast-conserving surgery: promises and pitfalls Journal Article
| Author: | Morrow, M. |
| Article Title: | Magnetic resonance imaging for screening, diagnosis, and eligibility for breast-conserving surgery: promises and pitfalls |
| Abstract: | Magnetic resonance imaging (MRI) is able to visualize small tumor deposits that previously could only be identified on pathologic examination. MRI is most valuable in areas in which patient management has been problematic, including screening women with known or suspected BRCA 1 and 2 mutations, and identification of the primary tumor site in patients presenting with axillary adenopathy. The role of MRI in the patient with newly diagnosed breast cancer remains controversial. Success rates for patients selected for breast-conserving therapy without MRI are high, and rates of ipsilateral breast tumor recurrence are low. Future efforts to improve the local therapy for breast cancer must acknowledge the heterogeneity of the disease and tailor approaches to the biology of individual subsets. This goal can only be accomplished through a multidisciplinary approach that examines the applications of newer diagnostic modalities such as MRI. © 2010 Elsevier Inc. |
| Keywords: | cancer survival; gene mutation; clinical trial; histopathology; review; cancer recurrence; cancer risk; patient selection; cancer radiotherapy; nuclear magnetic resonance imaging; recurrence risk; magnetic resonance imaging; lymph node dissection; diagnostic accuracy; sensitivity and specificity; organization and management; tumor localization; breast cancer; echomammography; mastectomy; tumor volume; epidermal growth factor receptor 2; cancer screening; breast neoplasms; brca1 protein; brca2 protein; prediction; axillary lymph node; patient care; mammography; diagnostic value; family history; breast tumor; partial mastectomy; intermethod comparison; estrogen receptor; progesterone receptor; false positive result; intraductal carcinoma; lymphadenopathy; segmental mastectomy; mastectomy, segmental; breast biopsy; individualization; breast-conserving therapy; occult cancer; local recurrence; eligibility determination |
| Journal Title: | Surgical Oncology Clinics of North America |
| Volume: | 19 |
| Issue: | 3 |
| ISSN: | 1055-3207 |
| Publisher: | Elsevier Inc. |
| Date Published: | 2010-07-01 |
| Start Page: | 475 |
| End Page: | 492 |
| Language: | English |
| DOI: | 10.1016/j.soc.2010.03.003 |
| PUBMED: | 20620922 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | --- - "Cited By (since 1996): 1" - "Export Date: 20 April 2011" - "CODEN: SOCAF" - "Source: Scopus" |
