Postoperative pain medication requirements in patients undergoing computer-assisted ("robotic") and standard laparoscopic procedures for newly diagnosed endometrial cancer Journal Article


Authors: Leitao, M. M. Jr; Malhotra, V.; Briscoe, G.; Suidan, R.; Dholakiya, P.; Santos, K.; Jewell, E. L.; Brown, C. L.; Sonoda, Y.; Abu-Rustum, N. R.; Barakat, R. R.; Gardner, G. J.
Article Title: Postoperative pain medication requirements in patients undergoing computer-assisted ("robotic") and standard laparoscopic procedures for newly diagnosed endometrial cancer
Abstract: Purpose: Laparoscopy (LSC) offers superior patient outcomes compared to laparotomy. Small retrospective/prospective series have suggested robotics offers further reduction in postoperative pain and pain medication use compared to standard LSC. Our objective was to compare postoperative pain in patients undergoing robotically assisted (RBT) versus standard LSC for newly diagnosed endometrial cancer. Methods: All preoperative endometrial cancer cases scheduled for RBT and LSC from May 1, 2007 to June 9, 2010 were identified. For this analysis, we only included cases not requiring conversion to laparotomy. All patients were offered intravenous (IV) patient-controlled analgesia (PCA) postoperatively. Intraoperative equivalent fentanyl doses (IEFDs) and pain scores in the postanesthesia care unit (PACU) were assessed. Results: IV PCA was used in 206 RBTs (86 %) and 208 LSCs (88 %). Median IEFD was 425 μg for LSCs and 500 μg for RBTs (P = 0.03). Median pain scores on PACU arrival were similar in both groups. Median highest pain score was 5 for LSCs and 4 for RBTs (P = 0.007). Linear regression demonstrated that the IEFD was not correlated with the highest pain score (R = 0.09; P = 0.07). Fentanyl was used postoperatively in 196 of 206 RBTs (95 %) and 187 of 208 LSCs (90 %). The total fentanyl doses were 242.5 (range 0-2705) μg and 380 (range 0-2625) μg, respectively (P < 0.001). The median hourly fentanyl doses were 16.7 (range 0-122.5) μg and 23.5 (range 0-132.4) μg, respectively (P = 0.005). Simultaneous multiple regression analysis further demonstrated RBT was independently associated with a lower total fentanyl dose compared to LSC (P = 0.02). Conclusions: RBT is independently associated with significantly lower postoperative pain and pain medication requirements compared to LSC. The amount of intraoperative fentanyl analgesia does not appear to correlate with postoperative pain. © 2013 Society of Surgical Oncology.
Journal Title: Annals of Surgical Oncology
Volume: 20
Issue: 11
ISSN: 1068-9265
Publisher: Springer  
Date Published: 2013-06-25
Start Page: 3561
End Page: 3567
Language: English
DOI: 10.1245/s10434-013-3064-9
PROVIDER: scopus
PUBMED: 23797751
DOI/URL:
Notes: --- - "Export Date: 1 October 2013" - "CODEN: ASONF" - "Source: Scopus"
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MSK Authors
  1. Ginger J Gardner
    270 Gardner
  2. Elizabeth Jewell
    131 Jewell
  3. Richard R Barakat
    629 Barakat
  4. Carol Brown
    167 Brown
  5. Yukio Sonoda
    472 Sonoda
  6. Mario Leitao
    575 Leitao
  7. Kevin Santos
    8 Santos
  8. Rudy Sam Joseph Suidan
    11 Suidan