Abstract: |
Compared to other species, such as the mouse and the rat, there are only very few viruses that have definitively been associated with the hamster and those that generally affect the Syrian hamster. The number of viruses found in laboratory rodents seems to be directly proportional to their popularity as experimental animals. Most rodent viruses and the hamster only produce subclinical infections in their hosts and were only discovered accidentally. Most viral infections in hamsters are clinically silent with the notable exception of the hamster polyomavirus and to a lesser degree the hamster parvovirus. These seem to be the only agents that consistently produce clinical disease and these viruses may actually not be natural pathogens of the Syrian hamster. However, despite the lack of clinical signs the agents described in this chapter may have a significant negative impact on the research that is conducted while using infected animals. The one hamster virus that has the most significant impact on human medicine is lymphocytic choriomeningitis virus (LCMV) due to its zoonotic potential. Although it is primarily a mouse virus, the hamster, albeit the pet hamster, is the most common animal species to transmit the virus to humans. © 2012 Elsevier Inc. All rights reserved. |