Synapse - Use of normal tissue complication probability models in the clinic

Use of normal tissue complication probability models in the clinic Journal Article

Authors:	Marks, L. B.; Yorke, E. D.; Jackson, A.; Ten Haken, R. K.; Constine, L. S.; Eisbruch, A.; Bentzen, S. M.; Nam, J.; Deasy, J. O.
Article Title:	Use of normal tissue complication probability models in the clinic
Abstract:	The Quantitative Analysis of Normal Tissue Effects in the Clinic (QUANTEC) review summarizes the currently available three-dimensional dose/volume/outcome data to update and refine the normal tissue dose/volume tolerance guidelines provided by the classic Emami et al. paper published in 1991. A "clinician's view" on using the QUANTEC information in a responsible manner is presented along with a description of the most commonly used normal tissue complication probability (NTCP) models. A summary of organ-specific dose/volume/outcome data, based on the QUANTEC reviews, is included. © 2010 Elsevier Inc. All rights reserved.
Keywords:	adult; child; treatment outcome; three dimensional; radiation dose; models, biological; practice guideline; radiation injury; dose-response relationship, radiation; mathematical model; radiation oncology; dosimetry; quantitative analysis; models, statistical; practice guidelines as topic; organ specificity; outpatient department; radiation injuries; dose fractionation; organ size; radiation dose distribution; normal tissue; mathematical analysis; radiation tolerance; quantec; ntcp; normal-tissue complication probability models
Journal Title:	International Journal of Radiation Oncology, Biology, Physics
Volume:	76
Issue:	3 Suppl.
ISSN:	0360-3016
Publisher:	Elsevier Inc.
Date Published:	2010-03-01
Start Page:	S10
End Page:	S19
Language:	English
DOI:	10.1016/j.ijrobp.2009.07.1754
PUBMED:	20171502
PROVIDER:	scopus
PMCID:	PMC4041542
DOI/URL:	http://www.scopus.com/inward/record.url?eid=2-s2.0-76449106780&partnerID=40&md5=7ee71f8b2bfca1355a2a9c3fb772fc71
Notes:	--- - "Cited By (since 1996): 6" - "Export Date: 20 April 2011" - "CODEN: IOBPD" - "Source: Scopus"

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MSK Authors

253 Jackson
450 Yorke

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