Authors: | Marks, L. B.; Bentzen, S. M.; Deasy, J. O.; Kong, F. M.; Bradley, J. D.; Vogelius, I. S.; El Naqa, I.; Hubbs, J. L.; Lebesque, J. V.; Timmerman, R. D.; Martel, M. K.; Jackson, A. |
Article Title: | Radiation dose - Volume effects in the lung |
Abstract: | The three-dimensional dose, volume, and outcome data for lung are reviewed in detail. The rate of symptomatic pneumonitis is related to many dosimetric parameters, and there are no evident threshold "tolerance dose-volume" levels. There are strong volume and fractionation effects. © 2010 Elsevier Inc. All rights reserved. |
Keywords: | cisplatin; gemcitabine; paclitaxel; radiation dose; antineoplastic agent; carboplatin; lung toxicity; biological model; models, biological; radiation; etoposide; lung neoplasms; radiotherapy dosage; lung cancer; radiation injury; risk factor; radiation response; mathematical model; docetaxel; dyspnea; pneumonia; lung tumor; radiation effects; dosimetry; radiation dose fractionation; models, statistical; comorbidity; lung; radiation hazard; biological organs; radiation pneumonia; pneumonitis; radiation tolerance; quantec; dose-volume; lung injury; lung volume; dosimetric parameter; fractionation effects; radiation pneumonitis |
Journal Title: | International Journal of Radiation Oncology, Biology, Physics |
Volume: | 76 |
Issue: | 3 Suppl. |
ISSN: | 0360-3016 |
Publisher: | Elsevier Inc. |
Date Published: | 2010-03-01 |
Start Page: | S70 |
End Page: | S76 |
Language: | English |
DOI: | 10.1016/j.ijrobp.2009.06.091 |
PUBMED: | 20171521 |
PROVIDER: | scopus |
PMCID: | PMC3576042 |
DOI/URL: | |
Notes: | --- - "Cited By (since 1996): 8" - "Export Date: 20 April 2011" - "CODEN: IOBPD" - "Source: Scopus" |