MAPping the genomic landscape of low-grade pediatric gliomas Journal Article

   

Authors:	Turcan, S.; Chan, T. A.
Article Title:	MAPping the genomic landscape of low-grade pediatric gliomas
Abstract:	Two recent large-scale sequencing studies have identified multiple genetic aberrations in pediatric low-grade gliomas. These findings offer substantial insights that may spur the development of new diagnostics and treatments for these cancers. © 2013 Nature America, Inc. All rights reserved.
Keywords:	mitogen activated protein kinase; protein expression; gene sequence; missense mutation; glioma; cancer grading; morbidity; in vitro study; protein tyrosine kinase; autophosphorylation; cancer mortality; childhood cancer; carcinogenesis; gene mapping; enzyme phosphorylation; genomics; dimerization; malignant transformation; pleomorphic xanthoastrocytoma; b raf kinase; fibroblast growth factor receptor 1; chromatin assembly and disassembly; histone modification; pilocytic astrocytoma; cancer prognosis; high throughput sequencing
Journal Title:	Nature Genetics
Volume:	45
Issue:	8
ISSN:	1061-4036
Publisher:	Nature Publishing Group
Date Published:	2013-08-01
Start Page:	847
End Page:	849
Language:	English
DOI:	10.1038/ng.2706
PROVIDER:	scopus
PUBMED:	23892663
PMCID:	PMC4916641
DOI/URL:	http://www.scopus.com/inward/record.url?eid=2-s2.0-84881017781&partnerID=40&md5=4d81200d07363b60478cba0a9fa9ea1b
Notes:	- "Export Date: 4 September 2013" - "CODEN: NGENE" - "Source: Scopus"

https://synapse.mskcc.org/synapse/works/has_related_data_chk/45518