A clear picture of renal cell carcinoma Journal Article
| Authors: | Hakimi, A. A.; Pham, C. G.; Hsieh, J. J. |
| Article Title: | A clear picture of renal cell carcinoma |
| Abstract: | Two recent studies describe the largest molecular profiling analyses to date of clear-cell renal cell carcinoma (ccRCC) and report remarkably similar findings. The recurrent pathway alterations identified in these studies open new avenues for therapeutic advances in this chemotherapy- and radiation-resistant disease. © 2013 Nature America, Inc. All rights reserved. |
| Keywords: | cancer chemotherapy; single nucleotide polymorphism; missense mutation; disease course; protein conformation; gene expression profiling; genetic association; genetic variability; mutational analysis; phosphatidylinositol 3 kinase; kidney carcinoma; algorithm; gene identification; mammalian target of rapamycin; radiosensitivity; heterozygosity loss; chromosome 8; chromosome analysis; metabolic disorder; transcriptome; glutamine; chromosome 3p; citric acid cycle; histone modification; hydroxymethylglutaryl coenzyme a reductase kinase; haploinsufficiency; elongin c |
| Journal Title: | Nature Genetics |
| Volume: | 45 |
| Issue: | 8 |
| ISSN: | 1061-4036 |
| Publisher: | Nature Publishing Group |
| Date Published: | 2013-08-01 |
| Start Page: | 849 |
| End Page: | 850 |
| Language: | English |
| DOI: | 10.1038/ng.2708 |
| PROVIDER: | scopus |
| PUBMED: | 23892664 |
| DOI/URL: | |
| Notes: | --- - "Export Date: 4 September 2013" - "CODEN: NGENE" - "Source: Scopus" |
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