NetPath: A public resource of curated signal transduction pathways Journal Article
| Authors: | Kandasamy, K.; Sujatha Mohan, S.; Raju, R.; Keerthikumar, S.; Sameer Kumar, G. S.; Venugopal, A. K.; Telikicherla, D.; Navarro, D. J.; Mathivanan, S.; Pecquet, C.; Gollapudi, S. K.; Tattikota, S. G.; Mohan, S.; Padhukasahasram, H.; Subbannayya, Y.; Goel, R.; Jacob, H. K.; Zhong, J.; Sekhar, R.; Nanjappa, V.; Balakrishnan, L.; Subbaiah, R.; Ramachandra, Y. L.; Abdul Rahiman, B.; Keshava Prasad, T. S.; Lin, J. X.; Houtman, J. C.; Desiderio, S.; Renauld, J. C.; Constantinescu, S.; Ohara, O.; Hirano, T.; Kubo, M.; Singh, S.; Khatri, P.; Draghici, S.; Bader, G. D.; Sander, C.; Leonard, W. J.; Pandey, A. |
| Article Title: | NetPath: A public resource of curated signal transduction pathways |
| Abstract: | We have developed NetPath as a resource of curated human signaling pathways. As an initial step, NetPath provides detailed maps of a number of immune signaling pathways, which include ~1,600 reactions annotated from the literature and more than 2,800 instances of transcriptionally-regulated genes - all linked to over 5,500 published articles. We anticipate NetPath to become a consolidated resource for human signaling pathways that should enable systems biology approaches. © 2010 Kandasamy et al. , licensee BioMed Central Ltd. |
| Keywords: | signal transduction; methodology; protein analysis; animal; metabolism; animals; interleukin 2; reverse transcription polymerase chain reaction; apoptosis; immune system; biological model; biology; computational biology; models, biological; internet; cell motion; genetic transcription; protein interaction; transcription, genetic; information retrieval; reference database; gene mapping; access to information; protein processing; transcription regulation; microarray analysis; cell movement; intermethod comparison; medical literature; models, genetic; computer program; factual database; databases, factual; protein interaction mapping; software; biochemistry; interleukin-2; systems biology; northern blotting; netpath; serial analysis of gene expression |
| Journal Title: | Genome Biology |
| Volume: | 11 |
| Issue: | 1 |
| ISSN: | 1465-6906 |
| Publisher: | Biomed Central Ltd |
| Date Published: | 2010-01-12 |
| Start Page: | R3 |
| Language: | English |
| DOI: | 10.1186/gb-2010-11-1-r3 |
| PUBMED: | 20067622 |
| PROVIDER: | scopus |
| PMCID: | PMC2847715 |
| DOI/URL: | |
| Notes: | --- - "Cited By (since 1996): 5" - "Export Date: 20 April 2011" - "Art. No.: r3" - "CODEN: GNBLF" - "Source: Scopus" |
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