Authors: | Sourati, J.; Kose, K.; Rajadhyaksha, M.; Dy, J. G.; Erdogmus, D.; Brooks, D. H. |
Title: | Automated localization of wrinkles and the dermo-epidermal junction in obliquely-oriented reectance confocal microscopic images of human skin |
Conference Title: | Photonic Therapeutics and Diagnostics IX |
Abstract: | Reflectance Confocal Microscopic (RCM) imaging of obliquely-oriented optical sections, rather than with traditional z-stacks, shows depth information that more closely mimics the appearance of skin in orthogonal sections of histology. This approach may considerably reduce the amount of data that must be acquired and processed. However, as with z-stacks, purely visual detection of the dermal-epidermal junction (DEJ) in oblique images remains challenging. Here, we have extended our original algorithm for localization of DEJ in z-stacks to oblique images. In addition, we developed an algorithm for detecting wrinkles, which in addition to its intrinsic merit, gives useful information for DEJ detection. © 2013 SPIE. |
Keywords: | algorithms; dermal-epidermal junctions; dermis/epidermis junction localization; obliquely-oriented sectioning; reectance confocal microscopy; wrinkles; confocal microscopic image; depth information; optical sections; original algorithms |
Journal Title | Proceedings of SPIE |
Volume: | 8565 |
Conference Dates: | 2013 Feb 2-7 |
Conference Location: | San Francisco, CA |
ISBN: | 0277-786X |
Publisher: | SPIE |
Location: | San Francisco, CA |
Date Published: | 2013-01-01 |
Start Page: | 856503 |
Language: | English |
PROVIDER: | scopus |
DOI: | 10.1117/12.2006489 |
DOI/URL: | |
Notes: | --- - Progress in Biomedical Optics and Imaging - Proceedings of SPIE - Progr. Biomed. Opt. Imaging Proc. SPIE - "Conference code: 97149" - "Export Date: 1 July 2013" - ":doi 10.1117/12.2006489" - "Sponsors: The Society of Photo-Optical Instrumentation Engineers (SPIE)" - 2 February 2013 through 7 February 2013 - "Source: Scopus" |