Detection of Plasmodium vivax in a child returning from India by use of broad-range PCR and electrospray ionization mass spectrometry Journal Article


Authors: Rounds, M. A.; Crowder, C. D.; Stratton, C. W.; Ecker, D. J.; Eshoo, M. W.; Tang, Y. W.
Article Title: Detection of Plasmodium vivax in a child returning from India by use of broad-range PCR and electrospray ionization mass spectrometry
Abstract: Plasmodium vivax is a common cause of imported malaria in the USA, second only to P. falciparum. We present a case of P. vivax malaria in a child returning from India. P. vivax was initially diagnosed by standard methodology and detected retrospectively by use of broad-range PCR and electrospray ionization mass spectrometry using a panel of primers designed to detect vector-borne pathogens. This is the first reported case of P. vivax detection using PCR and electrospray ionization mass spectrometry. © 2013 SSCC. All rights reserved.
Keywords: child; school child; treatment outcome; histopathology; pathogenesis; case report; diarrhea; polymerase chain reaction; vomiting; primaquine; retrospective study; coughing; fever; paracetamol; nucleotide sequence; disease duration; india; headache; physical examination; blood cell count; liver function test; diagnostic test; urinalysis; atovaquone; electrospray mass spectrometry; blood chemistry; atovaquone plus proguanil; pcr and electrospray ionization mass spectrometry; plasmodium vivax; proguanil; plasmodium vivax malaria
Journal Title: Emerging Microbes & Infections
Volume: 1
ISSN: 2222-1751
Publisher: Nature Publishing Group  
Date Published: 2012-01-01
Start Page: e48
Language: English
DOI: 10.1038/emi.2012.49
PROVIDER: scopus
PMCID: PMC3630909
PUBMED: 26038414
DOI/URL:
Notes: --- - "Export Date: 1 July 2013" - "Molecular Sequence Numbers: GENBANK: AF316892;" - "Source: Scopus"
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  1. Yi-Wei Tang
    188 Tang