Melanoma, version 2.2013 Journal Article
| Authors: | Coit, D. G.; Andtbacka, R.; Anker, C. J.; Bichakjian, C. K.; Carson, W. E.; Daud, A.; DiMaio, D.; Fleming, M. D.; Guild, V.; Halpern, A. C.; Hodi, F. S. Jr; Kelley, M. C.; Khushalani, N. I.; Kudchadkar, R. R.; Lange, J. R.; Lind, A.; Martini, M. C.; Olszanski, A. J.; Pruitt, S. K.; Ross, M. I.; Swetter, S. M.; Tanabe, K. K.; Thompson, J. A.; Trisal, V.; Urist, M. M.; McMillian, N.; Ho, M. |
| Article Title: | Melanoma, version 2.2013 |
| Abstract: | The NCCN Guidelines for Melanoma provide multidisciplinary recommendations on the clinical management of patients with melanoma. This NCCN Guidelines Insights report highlights notable recent updates. Foremost of these is the exciting addition of the novel agents ipilimumab and vemurafenib for treatment of advanced melanoma. The NCCN panel also included imatinib as a treatment for KIT-mutated tumors and pegylated interferon alfa-2b as an option for adjuvant therapy. Also important are revisions to the initial stratification of early-stage lesions based on the risk of sentinel lymph node metastases, and revised recommendations on the use of sentinel lymph node biopsy for low-risk groups. Finally, the NCCN panel reached clinical consensus on clarifying the role of imaging in the workup of patients with melanoma. Copyright © 2013 by the National Comprehensive Cancer Network. All rights reserved. |
| Keywords: | treatment response; cancer surgery; overall survival; disease course; cisplatin; placebo; advanced cancer; cancer combination chemotherapy; alpha interferon; paclitaxel; cancer adjuvant therapy; disease free survival; chemotherapy, adjuvant; temozolomide; cancer diagnosis; lymph node dissection; sentinel lymph node biopsy; imatinib; carboplatin; dacarbazine; interleukin 2; ipilimumab; peginterferon alpha2b; cancer immunotherapy; melanoma; liver toxicity; skin neoplasms; practice guideline; algorithms; skin carcinoma; vinblastine; societies, medical; disease progression; computer assisted emission tomography; practice guidelines as topic; education, medical, continuing; medical oncology; photosensitivity; granulocytopenia; keratoacanthoma; randomized controlled trial (topic); vemurafenib; therapies, investigational; cancer prognosis; sentinel lymph node metastasis; comprehensive health care; interferons |
| Journal Title: | Journal of the National Comprehensive Cancer Network |
| Volume: | 11 |
| Issue: | 4 |
| ISSN: | 1540-1405 |
| Publisher: | Harborside Press |
| Date Published: | 2013-04-01 |
| Start Page: | 395 |
| End Page: | 407 |
| Language: | English |
| PROVIDER: | scopus |
| PUBMED: | 23584343 |
| DOI/URL: | |
| Notes: | --- - "Export Date: 1 July 2013" - "Source: Scopus" |
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