Authors: | Holloway, C. L.; DeLaney, T. F.; Alektiar, K. M.; Devlin, P. M.; O'Farrell, D. A.; Demanes, D. J. |
Article Title: | American Brachytherapy Society (ABS) consensus statement for sarcoma brachytherapy |
Abstract: | Purpose: To present recommendations for the use of brachytherapy (BT) in patients with soft tissue sarcoma (STS). Methods: A group of practitioners with expertise and experience in sarcoma BT formulated recommendations for BT in STS based on clinical experience and literature review. Results: The indications for adjuvant BT are discussed. There is no consensus on the use of BT alone or in combination with external beam radiation therapy (EBRT), but factors that influence the selection of this modality include tumor grade and size, prior surgeries, and tumor recurrence. Low-dose-rate, high-dose-rate, and pulsed-dose-rate radiation are all acceptable BT modalities to use for STS. Recommendations are made for patient selection, techniques, dose rates, and dosages. Outcome data and toxicity data are reviewed. Conclusions: BT is a useful component of the treatment of STS. The advantages of BT are the targeted dose distribution, low integral dose, and short treatment times. Ultimately the clinician should select the modality or combination of modalities that are most familiar to the treatment team and suitable to the patient. © 2013 American Brachytherapy Society. |
Keywords: | treatment planning; united states; radiation dose; cancer staging; outcome assessment; recurrent cancer; cancer grading; consensus; radiotherapy dosage; radiation exposure; sarcoma; societies, medical; dosimetry; tumor recurrence; cancer size; reoperation; practice guidelines as topic; medical society; soft tissue sarcoma; brachytherapy; nerve injury; physician; external beam radiotherapy; radiation safety; wound healing impairment; radiation dose distribution; wound complication; iridium 192; catheter removal; consensus statement; bone injury; radiological procedures; retroperitoneal sarcoma; brachytherapy implant; catheter care |
Journal Title: | Brachytherapy |
Volume: | 12 |
Issue: | 3 |
ISSN: | 1538-4721 |
Publisher: | Elsevier Science, Inc. |
Date Published: | 2013-05-01 |
Start Page: | 179 |
End Page: | 190 |
Language: | English |
DOI: | 10.1016/j.brachy.2012.12.002 |
PROVIDER: | scopus |
PUBMED: | 23434220 |
DOI/URL: | |
Notes: | --- - "Export Date: 3 June 2013" - "CODEN: BRACC" - "Source: Scopus" |