Circulating tumor cells: A potential bladder Cancer biomarker? Journal Article
| Authors: | Gallagher, D. J.; Milowsky, M. I. |
| Article Title: | Circulating tumor cells: A potential bladder Cancer biomarker? |
| Abstract: | The development of biomarkers to determine prognosis and predict response to therapy is an active area of research and represents an important part of the ongoing effort to individualize cancer care. Circulating tumor cells (CTCs) have demonstrated promise in several malignancies including prostate, breast, and colon cancer, and are being investigated prospectively as a correlative endpoint in clinical trials. Circulating tumor cells are also detectable in patients with advanced bladder cancer. The current review summarizes the recent technological advances in the detection and characterization of CTCs as well as their potential as a clinically useful biomarker in the management of patients with bladder cancer. |
| Keywords: | immunohistochemistry; cancer chemotherapy; cancer survival; unclassified drug; clinical trial; review; cisplatin; doxorubicin; cancer combination chemotherapy; disease marker; gemcitabine; paclitaxel; methotrexate; biological marker; breast cancer; bladder cancer; vinblastine; prostate cancer; diagnostic value; biomarker; immunomagnetic separation; drug response; cystectomy; tumor cell; androgen receptor; abiraterone acetate; mdv 3100; urothelial cancer; circulating tumor cells; androgen receptor antagonist |
| Journal Title: | European Journal of Clinical and Medical Oncology |
| Volume: | 2 |
| Issue: | 1 |
| ISSN: | 1759-8958 |
| Publisher: | San Lucas Medical |
| Date Published: | 2010-02-01 |
| Start Page: | 105 |
| End Page: | 110 |
| Language: | English |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | --- - "Export Date: 20 April 2011" - "Source: Scopus" |
