Imaging of metastatic CNS neuroblastoma Journal Article

  


Authors: D'Ambrosio, N.; Lyo, J. K.; Young, R. J.; Haque, S. S.; Karimi, S.
Article Title: Imaging of metastatic CNS neuroblastoma
Abstract: OBJECTIVE. Although neuroblastoma is a common childhood malignancy, which frequently metastasizes, involvement of the CNS is rarely reported in the literature. However, over the past several years, we have encountered an increasing number of cases of metastatic neuroblastoma to the CNS. This metastatic potential and changing metastatic pattern may, in part, be due to advances in medical treatment, leading to prolonged survival. This article will review the common and uncommon manifestations of metastatic neuroblastoma with an emphasis on the skull, dura, brain, ventricles, and leptomeninges. CONCLUSION. Neuroblastoma has diverse manifestations including masquerading as primary neurologic disease. This disease must be considered in a child with any unexplained neurologic disorder. Realizing that neuroblastoma may represent the cause of neurologic disease in a child will lead to earlier diagnosis. © American Roentgen Ray Society.
Keywords: child; preschool child; school child; child, preschool; leukemia; major clinical study; bone metastasis; neuroimaging; brain neoplasms; magnetic resonance imaging; computer assisted tomography; differential diagnosis; tomography, x-ray computed; diagnostic imaging; periosteum; sarcoma; bone lesion; brain ventricle; infant; neuroblastoma; contrast enhancement; lymphoma; brain metastasis; dura mater; meningeal metastasis; central nervous system metastasis; parenchyma; diffusion tensor imaging; cns metastases; dural metastases; pediatric neuroradiology; skull metastases; epidural space; histiocytosis x; osteosclerosis; skull; skull suture
Journal Title: American Journal of Roentgenology
Volume: 194
Issue: 5
ISSN: 0361-803X
Publisher: American Roentgen Ray Society  
Date Published: 2010-05-01
Start Page: 1223
End Page: 1229
Language: English
DOI: 10.2214/ajr.09.3203
PUBMED: 20410407
PROVIDER: scopus
DOI/URL:

http://www.scopus.com/inward/record.url?eid=2-s2.0-77951963457&partnerID=40&md5=0716df129005f5f9af9d3db6b71c5814
Notes: --- - "Export Date: 20 April 2011" - "CODEN: AJROA" - "Source: Scopus"
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MSK Authors
  1. John Kyungjin Lyo
    39 Lyo
  2. Robert J Young
    229 Young
  3. Sasan Karimi
    115 Karimi
  4. Sofia S Haque
    149 Haque
  5. Nicholas D'ambrosio
    4 D'ambrosio
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