Authors: | Ross, A. G.; Townsend, S. D.; Danishefsky, S. J. |
Article Title: | Halocycloalkenones as diels-alder dienophiles. applications to generating useful structural patterns |
Abstract: | Halocycloalkenones are demonstrated to function as potent dienophiles in inter- and intramolecular Diels- Alder cycloadditions. We have found 2-brominated cycloalkenone dienophiles to be both highly endo selective and significantly more reactive than their nonhalogenated parent compounds. A method for the facile conversion of brominated cyclobutanone DA adducts to synthetically useful cyclopropyl functional handles is described. © 2012 American Chemical Society. |
Journal Title: | Journal of Organic Chemistry |
Volume: | 78 |
Issue: | 1 |
ISSN: | 0022-3263 |
Publisher: | American Chemical Society |
Date Published: | 2013-01-04 |
Start Page: | 204 |
End Page: | 210 |
Language: | English |
DOI: | 10.1021/jo302230m |
PROVIDER: | scopus |
PMCID: | PMC3543988 |
PUBMED: | 23151095 |
DOI/URL: | |
Notes: | --- - "Export Date: 1 March 2013" - "CODEN: JOCEA" - "Source: Scopus" |