Halocycloalkenones as diels-alder dienophiles. applications to generating useful structural patterns Journal Article

   


Authors: Ross, A. G.; Townsend, S. D.; Danishefsky, S. J.
Article Title: Halocycloalkenones as diels-alder dienophiles. applications to generating useful structural patterns
Abstract: Halocycloalkenones are demonstrated to function as potent dienophiles in inter- and intramolecular Diels- Alder cycloadditions. We have found 2-brominated cycloalkenone dienophiles to be both highly endo selective and significantly more reactive than their nonhalogenated parent compounds. A method for the facile conversion of brominated cyclobutanone DA adducts to synthetically useful cyclopropyl functional handles is described. © 2012 American Chemical Society.
Journal Title: Journal of Organic Chemistry
Volume: 78
Issue: 1
ISSN: 0022-3263
Publisher: American Chemical Society  
Date Published: 2013-01-04
Start Page: 204
End Page: 210
Language: English
DOI: 10.1021/jo302230m
PROVIDER: scopus
PMCID: PMC3543988
PUBMED: 23151095
DOI/URL:

http://www.scopus.com/inward/record.url?eid=2-s2.0-84874099881&partnerID=40&md5=8bfdb98a77b0bcd874994b4477763b0c
Notes: --- - "Export Date: 1 March 2013" - "CODEN: JOCEA" - "Source: Scopus"
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MSK Authors
  1. Samuel J Danishefsky
    539 Danishefsky
  2. Steven D Townsend
    9 Townsend
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