Metastatic breast cancer, version 1.2012: Featured updates to the NCCN guidelines Journal Article


Authors: Carlson, R. W.; Allred, D. C.; Anderson, B. O.; Burstein, H. J.; Edge, S. B.; Farrar, W. B.; Forero, A.; Giordano, S. H.; Goldstein, L. J.; Gradishar, W. J.; Hayes, D. F.; Hudis, C. A.; Isakoff, S. J.; Ljung, B. M. E.; Mankoff, D. A.; Marcom, P. K.; Mayer, I. A.; McCormick, B.; Pierce, L. J.; Reed, E. C.; Smith, M. L.; Soliman, H.; Somlo, G.; Theriault, R. L.; Ward, J. H.; Wolff, A. C.; Zellars, R.; Kumar, R.; Shead, D. A.
Article Title: Metastatic breast cancer, version 1.2012: Featured updates to the NCCN guidelines
Abstract: These NCCN Guidelines Insights highlight the important updates/changes specific to the management of metastatic breast cancer in the 2012 version of the NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) for Breast Cancer. These changes/updates include the issue of retesting of biomarkers (estrogen receptor, progesterone receptor, and human epidermal growth factor receptor 2) on recurrent disease, new information regarding first-line combination endocrine therapy for metastatic disease, a new section on monitoring of patients with metastatic disease, and new information on endocrine therapy combined with an mTOR inhibitor as a subsequent therapeutic option. © JNCCN - Journal of the National Comprehensive Cancer Network.
Keywords: signal transduction; cancer survival; overall survival; fatigue; review; cancer growth; diarrhea; recurrent cancer; metastasis; progression free survival; drug eruption; breast cancer; stomatitis; epidermal growth factor receptor 2; tumor markers, biological; patient monitoring; practice guideline; breast neoplasms; exemestane; temsirolimus; cancer hormone therapy; hyperglycemia; pneumonia; protein kinase inhibitors; algorithm; mammalian target of rapamycin; neoplasm metastasis; letrozole; cancer epidemiology; antineoplastic agents, hormonal; estrogen receptor; postmenopause; everolimus; decreased appetite; phase 3 clinical trial (topic); disease activity; tor serine-threonine kinases
Journal Title: Journal of the National Comprehensive Cancer Network
Volume: 10
Issue: 7
ISSN: 1540-1405
Publisher: Harborside Press  
Date Published: 2012-07-01
Start Page: 821
End Page: 829
Language: English
PROVIDER: scopus
PUBMED: 22773798
PMCID: PMC3753191
DOI: 10.6004/jnccn.2012.0086
DOI/URL:
Notes: --- - "Export Date: 4 February 2013" - "Source: Scopus"
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  1. Clifford Hudis
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