Authors: | Carlson, R. W.; Allred, D. C.; Anderson, B. O.; Burstein, H. J.; Edge, S. B.; Farrar, W. B.; Forero, A.; Giordano, S. H.; Goldstein, L. J.; Gradishar, W. J.; Hayes, D. F.; Hudis, C. A.; Isakoff, S. J.; Ljung, B. M. E.; Mankoff, D. A.; Marcom, P. K.; Mayer, I. A.; McCormick, B.; Pierce, L. J.; Reed, E. C.; Smith, M. L.; Soliman, H.; Somlo, G.; Theriault, R. L.; Ward, J. H.; Wolff, A. C.; Zellars, R.; Kumar, R.; Shead, D. A. |
Article Title: | Metastatic breast cancer, version 1.2012: Featured updates to the NCCN guidelines |
Abstract: | These NCCN Guidelines Insights highlight the important updates/changes specific to the management of metastatic breast cancer in the 2012 version of the NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) for Breast Cancer. These changes/updates include the issue of retesting of biomarkers (estrogen receptor, progesterone receptor, and human epidermal growth factor receptor 2) on recurrent disease, new information regarding first-line combination endocrine therapy for metastatic disease, a new section on monitoring of patients with metastatic disease, and new information on endocrine therapy combined with an mTOR inhibitor as a subsequent therapeutic option. © JNCCN - Journal of the National Comprehensive Cancer Network. |
Keywords: | signal transduction; cancer survival; overall survival; fatigue; review; cancer growth; diarrhea; recurrent cancer; metastasis; progression free survival; drug eruption; breast cancer; stomatitis; epidermal growth factor receptor 2; tumor markers, biological; patient monitoring; practice guideline; breast neoplasms; exemestane; temsirolimus; cancer hormone therapy; hyperglycemia; pneumonia; protein kinase inhibitors; algorithm; mammalian target of rapamycin; neoplasm metastasis; letrozole; cancer epidemiology; antineoplastic agents, hormonal; estrogen receptor; postmenopause; everolimus; decreased appetite; phase 3 clinical trial (topic); disease activity; tor serine-threonine kinases |
Journal Title: | Journal of the National Comprehensive Cancer Network |
Volume: | 10 |
Issue: | 7 |
ISSN: | 1540-1405 |
Publisher: | Harborside Press |
Date Published: | 2012-07-01 |
Start Page: | 821 |
End Page: | 829 |
Language: | English |
PROVIDER: | scopus |
PUBMED: | 22773798 |
PMCID: | PMC3753191 |
DOI: | 10.6004/jnccn.2012.0086 |
DOI/URL: | |
Notes: | --- - "Export Date: 4 February 2013" - "Source: Scopus" |