A splicing twist on metastasis Journal Article
| Authors: | Olson, O. C.; Joyce, J. A. |
| Article Title: | A splicing twist on metastasis |
| Abstract: | An oncogenic splice variant of the transcription factor KLF6 is associated with metastasis and poor survival in node-negative breast cancer patients and promotes the epithelial-to-mesenchymal transition by regulating Twist. |
| Keywords: | signal transduction; cancer chemotherapy; cancer survival; protein expression; unclassified drug; cancer recurrence; cancer risk; nonhuman; drug targeting; cancer patient; lymph nodes; lymphatic metastasis; protein function; disease association; breast cancer; small interfering rna; genetic variability; enzyme activity; breast neoplasms; uvomorulin; risk assessment; oncogene; cancer cell; neoplasm metastasis; alternative splicing; kruppel like factor 6; kruppel-like transcription factors; short survey; breast metastasis; rna splicing; epithelial-mesenchymal transition; tumor microenvironment; epithelial mesenchymal transition; molecular targeted therapy; kruppel like factor 6 variant 1; klf6 gene |
| Journal Title: | Science Translational Medicine |
| Volume: | 5 |
| Issue: | 169 |
| ISSN: | 1946-6234 |
| Publisher: | American Association for the Advancement of Science |
| Date Published: | 2013-01-01 |
| Start Page: | 169fs2 |
| Language: | English |
| DOI: | 10.1126/scitranslmed.3005424 |
| PROVIDER: | scopus |
| PUBMED: | 23345607 |
| DOI/URL: | |
| Notes: | --- - "Export Date: 1 February 2013" - "Source: Scopus" |
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