Molecular Diagnosis of Infection-Related Cancers in Dermatopathology Journal Article
| Author: | Pulitzer, M. |
| Article Title: | Molecular Diagnosis of Infection-Related Cancers in Dermatopathology |
| Abstract: | The association between viruses and skin cancer is increasingly recognized in a number of neoplasms, that is, cutaneous squamous cell carcinoma, Kaposi sarcoma, nasopharyngeal carcinoma, and Merkel cell carcinoma, as well as hematolymphoid malignancies such as adult T-cell leukemia/lymphoma and NK/T-cell lymphoma (nasal type) and post-transplant lymphoproliferative disorders. Molecular assays are increasingly used to diagnose and manage these diseases. In this review, molecular features of tumor viruses and related host responses are explored. The tests used to identify such features are summarized. Evaluation of the utility of these assays for diagnosis and/or management of specific tumor types is presented. © 2012 Frontline Medical Communications. |
| Keywords: | immunohistochemistry; histopathology; review; squamous cell carcinoma; nonhuman; skin cancer; skin carcinoma; t cell lymphoma; herpes virus; nasopharynx carcinoma; merkel cell carcinoma; merkel cell polyomavirus; merkel cell tumor; polyoma virus; human immunodeficiency virus; lymphoproliferative disease; virus infection; kaposi sarcoma; rna virus; t cell leukemia; epstein barr virus; human herpesvirus 8; retrovirus; wart virus; human t cell leukemia virus 1; nk t cell lymphoma; papilloma virus; molecular diagnosis; insertional mutagenesis; dna virus; epstein-barr virus; adult t-cell leukemia-lymphoma; oncogenic virus; skin neoplasm |
| Journal Title: | Seminars in Cutaneous Medicine and Surgery |
| Volume: | 31 |
| Issue: | 4 |
| ISSN: | 1085-5629 |
| Publisher: | W.B. Saunders Co-Elsevier Inc. |
| Date Published: | 2012-12-01 |
| Start Page: | 247 |
| End Page: | 257 |
| Language: | English |
| DOI: | 10.1016/j.sder.2012.10.001 |
| PROVIDER: | scopus |
| PUBMED: | 23174495 |
| DOI/URL: | |
| Notes: | --- - "Export Date: 2 January 2013" - "CODEN: SCMSF" - "Source: Scopus" |
