Addressing the envelope for gene delivery Journal Article
| Authors: | O'Reilly, R. J. |
| Article Title: | Addressing the envelope for gene delivery |
| Abstract: | In this issue of Blood, Zhou et al describe a strategy for modifying the envelope proteins of a lentiviral vector to display a single chain antibody fragment, or ScFv, specific for CD8 so that the lentiviral vector selectively binds to and transduces CD8+ T lymphocytes. |
| Keywords: | nonhuman; note; cancer patient; neoplasms; cd8 antigen; cd8+ t lymphocyte; cd8-positive t-lymphocytes; animals; allele; gene targeting; t lymphocyte receptor; dna modification; receptors, antigen, t-cell; lentivirus vector; cytotoxicity, immunologic; immunocompetent cell; single chain fragment variable antibody; hla system |
| Journal Title: | Blood |
| Volume: | 120 |
| Issue: | 22 |
| ISSN: | 0006-4971 |
| Publisher: | American Society of Hematology |
| Date Published: | 2012-11-22 |
| Start Page: | 4278 |
| End Page: | 4279 |
| Language: | English |
| DOI: | 10.1182/blood-2012-09-451476 |
| PROVIDER: | scopus |
| PUBMED: | 23175659 |
| DOI/URL: | |
| Notes: | --- - "Export Date: 2 January 2013" - "CODEN: BLOOA" - "Source: Scopus" |
