Addressing the envelope for gene delivery Journal Article


Authors: O'Reilly, R. J.
Article Title: Addressing the envelope for gene delivery
Abstract: In this issue of Blood, Zhou et al describe a strategy for modifying the envelope proteins of a lentiviral vector to display a single chain antibody fragment, or ScFv, specific for CD8 so that the lentiviral vector selectively binds to and transduces CD8+ T lymphocytes.
Keywords: nonhuman; note; cancer patient; neoplasms; cd8 antigen; cd8+ t lymphocyte; cd8-positive t-lymphocytes; animals; allele; gene targeting; t lymphocyte receptor; dna modification; receptors, antigen, t-cell; lentivirus vector; cytotoxicity, immunologic; immunocompetent cell; single chain fragment variable antibody; hla system
Journal Title: Blood
Volume: 120
Issue: 22
ISSN: 0006-4971
Publisher: American Society of Hematology  
Date Published: 2012-11-22
Start Page: 4278
End Page: 4279
Language: English
DOI: 10.1182/blood-2012-09-451476
PROVIDER: scopus
PUBMED: 23175659
DOI/URL:
Notes: --- - "Export Date: 2 January 2013" - "CODEN: BLOOA" - "Source: Scopus"
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  1. Richard O'Reilly
    507 O'Reilly