Infiltrative brainstem and cerebellar neurocytoma Journal Article
| Authors: | Ahmad, F.; Rosenblum, M. K.; Chamyan, G.; Sandberg, D. I. |
| Article Title: | Infiltrative brainstem and cerebellar neurocytoma |
| Abstract: | Neurocytomas are typically intraventricular in location, and extraventricular neurocytomas are uncommon. The authors report the unique case of a 15-year-old girl who was found to have a low-grade neurocytoma infiltrating the brainstem and cerebellum and spreading along the CSF pathways to the lateral and third ventricles. The patient underwent endoscopic third ventriculostomy to treat associated hydrocephalus, and biopsy specimens from intraventricular tumor nodules were obtained. Because of the low-grade pathology, the fact that the lesion was not amenable to resection, and the extensive radiation field required for radiation therapy, she has been treated conservatively with close follow-up. Over the course of almost 4 years since diagnosis, no additional treatment has been required. Neurocytoma with widespread infiltration of the brainstem and cerebellum has not been previously reported. © 1944-2012 American Association of Neurological Surgeons. |
| Keywords: | adolescent; cancer chemotherapy; case report; cancer radiotherapy; neuroimaging; nuclear magnetic resonance imaging; follow up; brain neoplasms; cancer grading; ki 67 antigen; cerebellum; computer assisted tomography; tumor volume; oncology; cerebrospinal fluid; conservative treatment; nuclear magnetic resonance spectroscopy; neuroepithelioma; neoplasm invasiveness; brain biopsy; anastomosis; cerebellar neoplasms; ataxia; brain stem; facial nerve paralysis; n acetylaspartic acid; synaptophysin; brain third ventricle; brainstem; lateral brain ventricle; obstructive hydrocephalus; neurocytoma |
| Journal Title: | Journal of Neurosurgery-Pediatrics |
| Volume: | 10 |
| Issue: | 5 |
| ISSN: | 1933-0707 |
| Publisher: | American Association of Neurological Surgeons |
| Date Published: | 2012-11-01 |
| Start Page: | 418 |
| End Page: | 422 |
| Language: | English |
| DOI: | 10.3171/2012.8.peds08286 |
| PROVIDER: | scopus |
| PUBMED: | 22938078 |
| DOI/URL: | |
| Notes: | --- - "Export Date: 3 December 2012" - "Source: Scopus" |
