Authors: | Wang, T. J. C.; Menda, Y.; Cheng, S. K.; Wu, C. C.; Lee, N. Y. |
Article Title: | New tracers PET in head and neck squamous cell carcinoma |
Abstract: | PET is commonly used in the evaluation and posttreatment management of head and neck squamous cell carcinoma. Although [ 18F]fluorodeoxyglucose is the most commonly used radiopharmaceutical, many other radiopharmaceuticals are under investigation to assess particular biologic characteristics such as hypoxia and tumor repopulation. In this review, the authors discuss new PET tracers that allow the biologic profiling of head and neck squamous cell carcinomas, including [ 18F]fluoromisonidazole, [ 18F] fluorothymidine, [ 18F]fluoromethyltyrosine, and epidermal growth factor receptor biomarkers. © 2012 Elsevier Inc. |
Keywords: | unclassified drug; review; erlotinib; nonhuman; positron emission tomography; cell proliferation; tumor volume; epidermal growth factor receptor; hypoxia; head and neck cancer; gefitinib; radiopharmaceutical agent; 1 fluoro 3 (2 nitro 1 imidazolyl) 2 propanol f 18; tracer; pet; fluoromisonidazole; head and neck squamous cell carcinoma; carbon 11; amino acid metabolism; fluorothymidine; copper diacetyl bis(n4 methylthiosemicarbazone); fluorine methyl tyrosine; fluoroazomycin arabinoside f18 |
Journal Title: | PET Clinics |
Volume: | 7 |
Issue: | 4 |
ISSN: | 1556-8598 |
Publisher: | Elsevier Inc. |
Date Published: | 2012-10-01 |
Start Page: | 431 |
End Page: | 441 |
Language: | English |
DOI: | 10.1016/j.cpet.2012.06.009 |
PROVIDER: | scopus |
DOI/URL: | |
Notes: | --- - "Export Date: 2 November 2012" - "Source: Scopus" |