Abstract: |
Follicular dendritic cell sarcoma of the liver is an uncommon pathologic entity, and only 5 cases have been reported previously. Herein, we report the first case, to our knowledge, of hepatic follicular dendritic cell sarcoma without evidence of Epstein-Barr virus infection. The patient is an elderly man who was found to have an incidental liver mass and then developed weight loss and fever. The diagnosis was based on the typical morphologic appearance of spindle cell proliferation associated with a brisk lymphoplasmacytic infiltrate and strong immunoreactivity to CD21 and CD35. Based on our experience and a review of the published reports, we summarize the clinical and pathologic features of hepatic follicular dendritic cell sarcoma and its surgical management. |
Keywords: |
human tissue; treatment outcome; aged; aged, 80 and over; clinical feature; case report; liver neoplasms; cell proliferation; gastrointestinal stromal tumors; diagnosis, differential; tumor markers, biological; weight reduction; pathology; immunoreactivity; fever; sarcoma; liver tumor; spindle cell; virus infection; incidental finding; leiomyosarcoma; lymphocytic infiltration; lobectomy; stomach neoplasms; epstein barr virus; herpesvirus 4, human; complement component c3d receptor; complement component c3b receptor; liver sarcoma; dendritic cells, follicular; liver follicular dendritic cell sarcoma
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