Prosthetic intervention in the era of microvascular reconstruction of the mandible - A retrospective analysis of functional outcome Journal Article


Authors: Teoh, K. H.; Patel, S.; Hwang, F.; Huryn, J. M.; Verbel, D.; Zlotolow, I. M.
Article Title: Prosthetic intervention in the era of microvascular reconstruction of the mandible - A retrospective analysis of functional outcome
Abstract: Purpose: The purpose of this retrospective study was to compare the functional outcomes of patients who had mandibular resection and reconstruction with and without prosthetic intervention, and to identify predictive factors that may have an impact on functional outcomes. Materials and Methods: Two hundred twenty head and neck cancer patients who had undergone mandibular resection and reconstruction with at least 6 months of postoperative convalescence formed the basis of this retrospective review. Patients who did not receive prosthetic intervention formed group I (n = 142); those who received prosthetic intervention formed group II (n = 78). Functional outcomes were measured using four individual assessments (nutritional status, swallowing, masticatory performance, and speech) and one that combined the information from these assessments, the global measure of functional outcome (GMFO). Statistical analyses were used to compare the baseline characteristics and functional outcome between groups I and II and to analyze independent predictors for GMFO. Results: Of the 220 patients reviewed, 78 (35%) had prosthetic intervention; group II patients had better individual functional outcome measures and GMFO. Use of a prosthesis remained associated with GMFO after controlling for other significant predictors; other independent predictors were xerostomia, number of remaining mandibular teeth, number of tooth-to-tooth contacts, type of reconstruction, flap interference, and tongue defect. Patients who had fewer mandibular teeth and received a smaller prosthesis had better overall outcome than patients who received a larger prosthesis. Conclusion: Patients who had prosthetic intervention after mandibular reconstruction had significantly better functional outcomes than patients who did not receive prosthetic intervention, even after adjusting for confounding variables.
Keywords: adolescent; adult; child; controlled study; aged; aged, 80 and over; middle aged; functional assessment; reconstructive surgical procedures; recovery of function; retrospective studies; major clinical study; review; postoperative period; carcinoma, squamous cell; surgical flaps; comparative study; logistic models; retrospective study; statistical analysis; head and neck cancer; xerostomia; multivariate analysis; analysis of variance; convalescence; tongue neoplasms; tongue; speech; mandible; mandibular neoplasms; mandible reconstruction; mandible resection; swallowing; nutrition; oral surgical procedures; tooth; mastication; dental prosthesis, implant-supported; mandible prosthesis; denture, complete, lower
Journal Title: International Journal of Prosthodontics
Volume: 18
Issue: 1
ISSN: 0893-2174
Publisher: Quintessence Publishing  
Date Published: 2005-01-01
Start Page: 42
End Page: 54
Language: English
PUBMED: 15754892
PROVIDER: scopus
DOI/URL:
Notes: --- - "Cited By (since 1996): 11" - "Export Date: 24 October 2012" - "Source: Scopus"
Citation Impact
MSK Authors
  1. Teoh H Khim
    2 Khim
  2. Joseph M Huryn
    84 Huryn
  3. Snehal G Patel
    322 Patel
  4. David A Verbel
    20 Verbel
  5. Freeman R Hwang
    3 Hwang