Primary chordoid meningioma of lung Journal Article
| Authors: | Rowsell, C.; Sirbovan, J.; Rosenblum, M. K.; Perez-Ordoñez, B. |
| Article Title: | Primary chordoid meningioma of lung |
| Abstract: | Primary meningiomas of the lung are rare. Most pulmonary meningiomas are typical syncytial or transitional meningiomas with smaller numbers of fibrous-type tumors. Herein, we report an unusual pulmonary tumor with the microscopic, immunohistochemical, and ultrastructural characteristics of a chordoid meningioma. The tumor was composed of cords and fascicles of small- to medium-sized spindle and epithelioid cells with eosinophilic cytoplasm and round nuclei with finely dispersed chromatin. The tumor cells were surrounded by an abundant mucoid, vacuolated stroma. The periphery of the tumor was enveloped by a significant lymphoplasmacytic infiltrate. The neoplastic cells were positive for vimentin and epithelial membrane antigen only. The unusual morphology of the tumor caused significant diagnostic difficulties. The differential diagnosis included inflammatory myofibroblastic tumor, spindle cell myoepithelioma, and extraskeletal myxoid chondrosarcoma. To the best of our knowledge, this is possibly the first description of an extracranial or intrapulmonary chordoid meningioma. © Springer-Verlag 2005. |
| Keywords: | immunohistochemistry; adult; human tissue; treatment outcome; middle aged; microscopy; case report; postoperative period; follow up; computer assisted tomography; diagnosis, differential; lung lobectomy; lung neoplasms; differential diagnosis; lung tumor; statistical significance; meningeal neoplasms; lung; bronchoscopy; thorax radiography; meningioma; inflammatory infiltrate; spindle cell carcinoma; epithelioid cell; chondrosarcoma; myxoma; epithelial membrane antigen; vimentin; microscopy, electron, transmission; myoepithelioma; plasma cell granuloma; cell ultrastructure; chordoid meningioma; primary chordoid meningioma |
| Journal Title: | Virchows Archiv |
| Volume: | 446 |
| Issue: | 3 |
| ISSN: | 0945-6317 |
| Publisher: | Springer |
| Date Published: | 2005-03-01 |
| Start Page: | 333 |
| End Page: | 337 |
| Language: | English |
| DOI: | 10.1007/s00428-004-1192-0 |
| PUBMED: | 15714337 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | --- - "Cited By (since 1996): 10" - "Export Date: 24 October 2012" - "CODEN: VARCE" - "Source: Scopus" |
