Antiviral T cell responses: Phalanx or multipronged attack? Journal Article
| Authors: | Posnett, D. N.; Engelhorn, M. E.; Houghton, A. N. |
| Article Title: | Antiviral T cell responses: Phalanx or multipronged attack? |
| Abstract: | Around 700 BCE, a new military formation called the phalanx was established in ancient Greece: a tight column of heavy infantry carrying long spears, or pikes, used in a single prong of attack. Later, in the battle of Marathon described by Herodotus, the Greeks learned the advantages of multipronged attacks, a strategy still used in modern warfare. Is the immune system similar in its approach to combating pathogens or tumors? JEM © The Rockefeller University Press. |
| Keywords: | review; nonhuman; neoplasms; cd8 antigen; antigen expression; cd8-positive t-lymphocytes; immune system; gene expression; genetic variability; cytotoxicity; experimental mouse; history; rna; t lymphocyte receptor; cytokine; antigen presentation; correlation analysis; cellular immunity; immune response; receptors, antigen, t-cell; major histocompatibility antigen class 2; vaccination; epitope; cytotoxic t lymphocyte; phosphoproteins; outcomes research; tumor immunity; cytokine production; virus infection; cd4 antigen; antigens, cd; mouse strain; cytotoxic t lymphocyte antigen 4; major histocompatibility complex; infection control; influenza; immediate-early proteins; herpes simplex virus; antigen presenting cell; viral matrix proteins; t lymphocyte activation; complementary dna; antiviral activity; antigens, differentiation; genetic heterogeneity; virus protein; viral proteins; major histocompatibility antigen class 1; immunity, cellular; tumor immunology; viremia; infection resistance; antigen antibody reaction; human cytomegalovirus; protein engineering; cytomegalovirus infections; immunobiology; glycoprotein b; polyclonal activation |
| Journal Title: | Journal of Experimental Medicine |
| Volume: | 201 |
| Issue: | 12 |
| ISSN: | 0022-1007 |
| Publisher: | Rockefeller University Press |
| Date Published: | 2005-06-20 |
| Start Page: | 1881 |
| End Page: | 1884 |
| Language: | English |
| DOI: | 10.1084/jem.20050928 |
| PUBMED: | 15967819 |
| PROVIDER: | scopus |
| PMCID: | PMC2212042 |
| DOI/URL: | |
| Notes: | --- - "Cited By (since 1996): 4" - "Export Date: 24 October 2012" - "CODEN: JEMEA" - "Source: Scopus" |
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