Cross-recognition of N-formylmethionine peptides is a general characteristic of H2-M3-restricted CD8+ T cells Journal Article


Authors: Ploss, A.; Tran, A.; Menet, E.; Leiner, I.; Pamer, E. G.
Article Title: Cross-recognition of N-formylmethionine peptides is a general characteristic of H2-M3-restricted CD8+ T cells
Abstract: H2-M3-restricted CD8+ T cells can exhibit cross-reactivity to different bacterially derived N-formylmethionine peptides. The extent of this promiscuity is unclear. We deleted the nonredundant fMIVTLF epitope and found that Listeria monocytogenes still primed fMIVTLF-specific T cells. Thus, cross-reactivity appears to be a more general characteristic of H2-M3-restricted T cells. Copyright © 2005, American Society for Microbiology. All Rights Reserved.
Keywords: controlled study; pathogenesis; nonhuman; cd8 antigen; cd8-positive t-lymphocytes; animal cell; mouse; animals; mice; protein protein interaction; animal experiment; animal model; mice, inbred c57bl; epitope; histocompatibility antigens class i; cross reaction; hermes antigen; t lymphocyte subpopulation; t lymphocyte activation; listeriosis; listeria monocytogenes; interleukin 2 receptor alpha; major histocompatibility antigen class 1; bacterial immunity; epitopes; padgem protein; cd69 antigen; p selectin glycoprotein ligand 1; cross reactions; formylmethionine; n-formylmethionine
Journal Title: Infection and Immunity
Volume: 73
Issue: 7
ISSN: 0019-9567
Publisher: American Society for Microbiology  
Date Published: 2005-07-01
Start Page: 4423
End Page: 4426
Language: English
DOI: 10.1128/iai.73.7.4423-4426.2005
PUBMED: 15972542
PROVIDER: scopus
PMCID: PMC1168546
DOI/URL:
Notes: --- - "Cited By (since 1996): 5" - "Export Date: 24 October 2012" - "CODEN: INFIB" - "Source: Scopus"
Altmetric Score
MSK Authors
  1. Alexander Ploss
    7 Ploss
  2. Ewa Menet
    3 Menet
  3. Eric Pamer
    249 Pamer
  4. Ingrid Leiner
    45 Leiner
  5. An Tran
    1 Tran