Cross-recognition of N-formylmethionine peptides is a general characteristic of H2-M3-restricted CD8+ T cells Journal Article
| Authors: | Ploss, A.; Tran, A.; Menet, E.; Leiner, I.; Pamer, E. G. |
| Article Title: | Cross-recognition of N-formylmethionine peptides is a general characteristic of H2-M3-restricted CD8+ T cells |
| Abstract: | H2-M3-restricted CD8+ T cells can exhibit cross-reactivity to different bacterially derived N-formylmethionine peptides. The extent of this promiscuity is unclear. We deleted the nonredundant fMIVTLF epitope and found that Listeria monocytogenes still primed fMIVTLF-specific T cells. Thus, cross-reactivity appears to be a more general characteristic of H2-M3-restricted T cells. Copyright © 2005, American Society for Microbiology. All Rights Reserved. |
| Keywords: | controlled study; pathogenesis; nonhuman; cd8 antigen; cd8-positive t-lymphocytes; animal cell; mouse; animals; mice; protein protein interaction; animal experiment; animal model; mice, inbred c57bl; epitope; histocompatibility antigens class i; cross reaction; hermes antigen; t lymphocyte subpopulation; t lymphocyte activation; listeriosis; listeria monocytogenes; interleukin 2 receptor alpha; major histocompatibility antigen class 1; bacterial immunity; epitopes; padgem protein; cd69 antigen; p selectin glycoprotein ligand 1; cross reactions; formylmethionine; n-formylmethionine |
| Journal Title: | Infection and Immunity |
| Volume: | 73 |
| Issue: | 7 |
| ISSN: | 0019-9567 |
| Publisher: | American Society for Microbiology |
| Date Published: | 2005-07-01 |
| Start Page: | 4423 |
| End Page: | 4426 |
| Language: | English |
| DOI: | 10.1128/iai.73.7.4423-4426.2005 |
| PUBMED: | 15972542 |
| PROVIDER: | scopus |
| PMCID: | PMC1168546 |
| DOI/URL: | |
| Notes: | --- - "Cited By (since 1996): 5" - "Export Date: 24 October 2012" - "CODEN: INFIB" - "Source: Scopus" |
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