Malignant ectomesenchymoma in the wrist of a child: Case report and review of the literature Journal Article


Authors: Oppenheimer, O.; Athanasian, E.; Meyers, P.; Antonescu, C. R.; Gorlick, R.
Article Title: Malignant ectomesenchymoma in the wrist of a child: Case report and review of the literature
Abstract: Malignant ectomesenchymomas, rare and potentially aggressive tumors, occur in children and exhibit mesenchymal and neuroectodermal components. This report describes the first patient diagnosed with a malignant ectomesenchymoma of the hand. The patient was a 17-month-old male who developed a hypothenar mass on his left hand that was surgically excised. Microscopic evaluation revealed ganglioneuroblastic, rhabdomyosarcomatous, and chondrosarcomatous elements. Following excisional biopsy he was treated with cyclophosphamide, doxorubicin, vincristine, ifosfamide, and etoposide. After 3 courses of chemotherapy the patient had a wide reexcision with no residual tumor. The patient is 4 years from diagnosis, without evidence of disease.
Keywords: disease-free survival; cancer surgery; histopathology; review; microscopy; case report; doxorubicin; cancer combination chemotherapy; chemotherapy; etoposide; antineoplastic combined chemotherapy protocols; cyclophosphamide; vincristine; tumor biopsy; ifosfamide; infant; neuroblastoma; reoperation; malignant neoplastic disease; rhabdomyosarcoma; chondrosarcoma; neuroectoderm tumor; pediatric tumors; soft tissue neoplasms; hand; wrist; mesenchymoma; malignant ectomesenchymoma
Journal Title: International Journal of Surgical Pathology
Volume: 13
Issue: 1
ISSN: 1066-8969
Publisher: Sage Publications  
Date Published: 2005-01-01
Start Page: 113
End Page: 116
Language: English
PUBMED: 15735865
PROVIDER: scopus
DOI/URL:
Notes: --- - "Cited By (since 1996): 3" - "Export Date: 24 October 2012" - "CODEN: IJSPF" - "Source: Scopus"
Citation Impact
MSK Authors
  1. Richard G Gorlick
    121 Gorlick
  2. Cristina R Antonescu
    897 Antonescu
  3. Paul Meyers
    311 Meyers
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