Hodgkin's lymphoma associated with plasma cell neoplasia: Cytological features and review of the literature Journal Article
| Authors: | Oliai, B. R.; Zakowski, M. F.; Lin, O. |
| Article Title: | Hodgkin's lymphoma associated with plasma cell neoplasia: Cytological features and review of the literature |
| Abstract: | Hodgkin's lymphoma (HL) associated with plasma cell neoplasia is extremely rare. Here, we report one case diagnosed by fine-needle aspiration biopsy (FNAB) and review the clinical features of 15 previously reported cases. Our specimen was obtained by FNAB of an enlarged right inguinal lymph node. Air-dried Diff-Quik (DQ)-stained slides and alcohol-fixed slides stained with hematoxylin-eosin (H&E) and Papanicolaou stains were reviewed. The specimen was cellular, consisting of lymphocytes and plasma cells. Flow cytometric analysis revealed a monoclonal (M) plasma-cell population. Admixed large atypical mono- and binucleated cells immunoreactive for CD30 were noted also. A diagnosis of plasma-cell neoplasm associated with classic HL was confirmed histologically after surgical removal of the lymph node. The diagnosis of both HL and plasma-cell neoplasia in the same patient is exceedingly rare. Adding another case to the 75 previously reported cases was unique because our case was diagnosed through FNAB. © 2005 Wiley-Liss, Inc. |
| Keywords: | immunohistochemistry; adult; human tissue; middle aged; clinical feature; review; case report; flow cytometry; lymph node dissection; lymph nodes; cytology; disease association; aspiration; tumor markers, biological; plasmacytoma; cell population; immunoreactivity; hodgkin disease; plasma cell; biopsy, fine-needle; alcohol; lymphoma; eosin; hematoxylin; inguinal lymph node; aspiration biopsy; lymphocyte; neoplasms, multiple primary; rare disease; cd30 antigen; papanicolaou test; neoplasia; hodgkin |
| Journal Title: | Diagnostic Cytopathology |
| Volume: | 33 |
| Issue: | 3 |
| ISSN: | 8755-1039 |
| Publisher: | Wiley Liss |
| Date Published: | 2005-09-01 |
| Start Page: | 181 |
| End Page: | 186 |
| Language: | English |
| DOI: | 10.1002/dc.20213 |
| PUBMED: | 16078251 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | --- - "Export Date: 24 October 2012" - "CODEN: DICYE" - "Source: Scopus" |
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