Adjuvant therapy for colon cancer in the elderly: Treat or don't treat? Journal Article

  


Authors: Levitz, J. S.; Lichtman, S. M.
Article Title: Adjuvant therapy for colon cancer in the elderly: Treat or don't treat?
Abstract: The changing demographics of the population have emphasized the importance of the care of older cancer patients. Many recent advances have also occurred in the treatment of colon cancer, particularly in the role of adjuvant therapy. These changes have included the addition of new drugs and schedules and the increasing recognition that older patients benefit from adjuvant therapy. In facing a decision regarding which particular regimen to use in the older patient, clinicians must take into account individual patient needs, comorbidities, cognitive function, and social supports. This article will review the adjuvant regimens and how they can be applied to the treatment of older patients. © 2005 Elsevier Inc. All rights reserved.
Keywords: treatment outcome; clinical trial; drug tolerability; neutropenia; review; fluorouracil; cancer combination chemotherapy; diarrhea; dose response; drug efficacy; drug safety; capecitabine; colorectal cancer; bolus injection; nephrotoxicity; leukopenia; mucosa inflammation; nausea; stomatitis; thrombocytopenia; vomiting; peripheral neuropathy; carcinoembryonic antigen; irinotecan; social support; cytidine deaminase; folinic acid; colon cancer; adjuvant chemotherapy; comorbidity; drug clearance; cognition; sepsis; aging; sex difference; drug metabolism; oxaliplatin; hand foot syndrome; alopecia; elderly care; socioeconomics; thymidine phosphorylase; hematologic disease; levamisole; drug preference; carboxylesterase
Journal Title: Community Oncology
Volume: 2
Issue: 4
ISSN: 1548-5315
Publisher: Elsevier Inc.  
Date Published: 2005-07-01
Start Page: 331
End Page: 336
Language: English
PROVIDER: scopus
DOI/URL:

http://www.scopus.com/inward/record.url?eid=2-s2.0-23344442458&partnerID=40&md5=ecca3598bb6771297357888de0d822d1
Notes: --- - "Cited By (since 1996): 3" - "Export Date: 24 October 2012" - "Source: Scopus"