Salvage surgery for locoregional recurrence following local excision Journal Article
| Authors: | Landmann, R. G.; Weiser, M. R. |
| Article Title: | Salvage surgery for locoregional recurrence following local excision |
| Abstract: | Recurrence following local excision of early rectal cancer has traditionally been considered innocuous and readily amenable to salvage resection, with little impact on overall survival. Recent studies have reported that this notion is incorrect, however. Unlike the primary rectal lesion confined to the intestinal wall, locoregional recurrence following local excision is generally advanced when detected. Salvage surgery often requires extended resections, and in some cases total pelvic exenteration with significant morbidity. Even when salvage surgery is successful at eradicating disease, local control and cure are not assured. It is apparent that the relatively high recurrence rates noted following local excision cannot be compensated for by simple salvage surgery at time of relapse. Improvements in patient selection and identification of micrometastatic disease are necessary to properly select patients for curative local excision, and to avoid locoregional relapse altogether. © 2005 Elsevier Inc. All rights reserved. |
| Keywords: | survival; cancer survival; cancer surgery; treatment failure; clinical trial; cancer localization; salvage therapy; advanced cancer; patient selection; cancer adjuvant therapy; cancer radiotherapy; recurrent cancer; antineoplastic agent; cancer diagnosis; cancer prevention; metastasis; morbidity; relapse; recurrence; prediction; prostate cancer; cancer size; computer assisted emission tomography; pelvis exenteration; convalescence; rectum cancer; pelvis cancer; sacrum; rectal cancer; rectum abdominoperineal resection; vagina cancer; local excision; salvage surgery; locoregional relapse; intestine wall |
| Journal Title: | Seminars in Colon and Rectal Surgery |
| Volume: | 16 |
| Issue: | 1 |
| ISSN: | 1043-1489 |
| Publisher: | Elsevier Inc. |
| Date Published: | 2005-03-01 |
| Start Page: | 36 |
| End Page: | 39 |
| Language: | English |
| DOI: | 10.1053/j.scrs.2005.05.002 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | --- - "Cited By (since 1996): 1" - "Export Date: 24 October 2012" - "CODEN: SCRSF" - "Source: Scopus" |
Altmetric
Citation Impact
BMJ Impact Analytics
Related MSK Work